Evidence map›Paper›PMID 41186673›Full record

ArticleInternational orthopaedics2026

Osseointegration of threaded acetabular cups - radiological and histological evaluation after total hip arthroplasty.

Elisabeth M Mandler, Peter Lorenz, Stephanie Huber, Jochen G Hofstaetter, Lena Hirtler, Gilbert M Schwarz

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Article in International orthopaedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Elisabeth M MandlerCenter for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Peter LorenzCenter for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Stephanie HuberMichael Ogon Laboratory for Orthopaedic Research, Orthopaedic Hospital Speising, Vienna, Austria.
Jochen G Hofstaetter2nd Department, Orthopaedic Hospital Speising, Vienna, Austria.
Lena HirtlerCenter for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria. lena.hirtler@meduniwien.ac.at.
Gilbert M SchwarzDepartment for Orthopaedic and Trauma Surgery, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAseptic loosening of the acetabular cup component is the primary cause for complex revision surgery following total hip arthroplasty. However, the extent to which the different zones of the prosthetic contribute to successful osseointegration and how reliable this integration can be assessed using conventional radiographs remain unclear. The aim of the study was to evaluate the osseointegration of cementless threaded acetabular cups through a combination of radiological analysis and histological validation.

methodsEight hemipelves of body donors with cementless threaded acetabular cups were included in this study. Conventional radiographs were used to assess the specimens for existing radiolucent lines, periprosthetic osteolysis, or fractures. For histological analysis, thin sections of the acetabular cup were examined for the presence of a periprosthetic membrane, particle debris or inflammatory cells. The areas of visible contact were identified and the bone-to-implant contact (BIC) was calculated.

resultsRadiographic analysis revealed no signs of insufficient osseointegration, osteolytic lesions, or periprosthetic loosening, in any of the specimens. Histological examination showed an average osseointegration rate of 41.84%. Bone-to-implant contact analysis showed no significant differences between different sectors or zones, or between conical and bi-conical acetabular cups.

conclusionThis study highlights successful osseointegration of cementless threaded acetabular cups, with a mean survival of 18.2 years. Radiological imaging aligned closely to histological finding, confirming implant stability and long-term clinical effectiveness.

Indexed as

AcetabulumArthroplasty, Replacement, HipHip JointHip ProsthesisOsseointegrationAdultAgedFemaleHumansMaleMiddle AgedProsthesis DesignProsthesis FailureRadiographyReoperationCementless threaded acetabular cupsOsseointegrationTotal hip arthroplasty

Identifiers

PMID41186673
PMCPMC12880993

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.