Evidence map›Paper›PMID 41186209›Full record

ArticleClinical transplantation2025

Adult Dual Kidney Transplantation Following Dual Renal Endarterectomy: A Case Series.

Arianna Cabrales, Jigish Vyas, Giuseppe Orlando, Christopher Webb, Alan C Farney, Robert J Stratta

Abstract readCase Reports
In one paragraph

Article in Clinical transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arianna CabralesDepartment of Surgery, Section of Transplantation, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, North Carolina, USA.
Jigish VyasDepartment of Surgery, Section of Transplantation, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, North Carolina, USA.
Giuseppe OrlandoDepartment of Surgery, Section of Transplantation, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, North Carolina, USA.
Christopher WebbDepartment of Surgery, Section of Transplantation, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, North Carolina, USA.
Alan C FarneyDepartment of Surgery, Section of Transplantation, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, North Carolina, USA.
Robert J StrattaDepartment of Surgery, Section of Transplantation, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, North Carolina, USA.ORCID https://orcid.org/0000-0001-7634-094X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDual kidney transplantation (DKT) represents a method of expanding the donor pool and minimizing kidney nonutilization. For kidneys with severe renal artery atherosclerosis, back-bench eversion endarterectomy (EE) may be performed as a salvage procedure to further promote utilization.

methodsWe report five cases of DKT in which both kidneys underwent EE prior to implantation.

resultsMean donor age was 60.2 ± 5.5 years, mean KDPI 84 ± 15%, and mean terminal serum creatinine 0.88 ± 0.3 mg/dL. There were three expanded criteria and three donations after circulatory death donors. All but one kidney was managed with hypothermic machine preservation (five with suboptimal pump parameters) and two were imported. Percentage glomerulosclerosis on biopsy ranged from 7% to 30% and cold ischemia times from 19.2 to 33.5 h. Mean recipient age was 63.0 ± 6.5 years, mean EPTS 65 ± 30%, and mean dialysis duration 19 ± 10.3 months. All recipients were chosen based on out-of-sequence allocation (median match run sequence #1480). Operating times ranged from 4 to 7 h; three cases were performed as unilateral and two bilateral extraperitoneal transplants. Three patients experienced delayed graft function; initial length of hospital stay ranged from 3 to 7 days. At 6 months follow-up, mean serum creatinine was 1.6 ± 0.3 mg/dL and GFR 46 ± 17 mL/min/1.73m

conclusionBased on this preliminary experience, we believe that acceptable outcomes can be achieved with DKT in appropriately selected cases, even in the setting of severe donor renal artery atherosclerosis requiring dual endarterectomy.

Indexed as

EndarterectomyKidney Failure, ChronicKidney TransplantationRenal ArteryRenal Artery ObstructionTissue DonorsAdultAgedFemaleFollow-Up StudiesGlomerular Filtration RateGraft SurvivalHumansKidney Function TestsMaleMiddle Ageddelayed graft functiondual kidney transplantdual renal endarterectomyexpanded criteria donorskidney nonutilizationmarginal deceased donors

Identifiers

PMID41186209
PMCPMC12584158

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.