Evidence map›Paper›PMID 41186153›Full record

ArticleNanoscale2025

Supramolecular assembly of unstructured peptides into rigid bundlemer polymers.

Joshua E Meisenhelter, Matthew Langenstein, Jacquelyn E Blum, Dai-Bei Yang, Darrin J Pochan, Jeffery G Saven, Christopher J Kloxin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joshua E MeisenhelterDepartment of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy Street, Newark, DE 19716, USA. cjk@udel.edu.ORCID http://orcid.org/0009-0001-6330-0364
Matthew LangensteinDepartment of Materials Science and Engineering, University of Delaware, 201 DuPont Hall, Newark, DE 19716, USA.ORCID http://orcid.org/0000-0002-8742-111X
Jacquelyn E BlumDepartment of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, PA 19104, USA. saven@sas.upenn.edu.
Dai-Bei YangDepartment of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, PA 19104, USA. saven@sas.upenn.edu.ORCID http://orcid.org/0009-0009-3327-6920
Darrin J PochanDepartment of Materials Science and Engineering, University of Delaware, 201 DuPont Hall, Newark, DE 19716, USA.ORCID http://orcid.org/0000-0002-0454-2339
Jeffery G SavenDepartment of Chemistry, University of Pennsylvania, 231 S. 34th Street, Philadelphia, PA 19104, USA. saven@sas.upenn.edu.ORCID http://orcid.org/0000-0001-5027-7241
Christopher J KloxinDepartment of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy Street, Newark, DE 19716, USA. cjk@udel.edu.ORCID http://orcid.org/0000-0002-1679-0022

Funding

This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2014 to 2024
$26.8M
NIGMS NIH HHS P20 GM104316
6 · The paper itself

Abstract

Unstructured, designed 15-residue peptide sequences conjugated between their N-termini through thiol-maleimide click chemistry yield coiled-coil, rod-like polymers with widths of 2 nm and lengths exceeding 5 μm. The assembly process enables supramolecular polymer formation and is distinct from previously reported step-growth polymerization of well-structured coiled coils.

Indexed as

PeptidesPolymersClick ChemistryMaleimidesPolymerizationmaleimideMaleimidesPeptidesPolymers

Identifiers

PMID41186153
PMCPMC12584133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.