ArticleVeterinary clinical pathology2025
Analytical Validation of a Novel Point-Of-Care Quantitative Immunoassay for Feline N-Terminal Pro-Brain Natriuretic Peptide.
Article in Veterinary clinical pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Diagnostic performance of Vcheck NT-proBNP and cardiac troponin I assays for detection of dilated cardiomyopathy in Doberman Pinschers.Frontiers in veterinary science · 2026Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPoint-of-care testing (POC) is widely utilized for rapid results for many different analytes. A new feline-specific N-terminal pro-brain natriuretic peptide (NT-proBNP) quantitative assay (Vcheck V200, Bionote Inc) is currently available but has not undergone independent validation.
objectiveTo validate the Vcheck POC quantitative assay for feline NT-proBNP.
methodsValidation was performed in accordance with the American Society for Veterinary Clinical Pathology guidelines utilizing serum samples from 62 cats. Precision was determined for low (50-100 pmol/L), mid (101-300 pmol/L), and high (> 301 pmol/L) pools short-term (20 repetitions) and long-term (5 repetitions each day for 5 days). Linearity, methods comparison, interference testing, and sample stability were evaluated.
resultsThe within-day coefficients of variability (CV) were low pool = 12.6%, mid pool = 10.4%, and high pool = 8.7%. The within-week CV was low pool = 9.9%, mid pool = 14.9%, and high pool = 6.9%. The assay was linear over the analytical range of 53-1488 pmol/L (R
conclusionsThe Vcheck V200 has acceptable precision, accuracy, and compares favorably with commercially available assays and is a viable POC quantitative assay for feline NT-proBNP.
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