Evidence map›Paper›PMID 41185877›Full record

ArticleCureus2025

Non-parathyroid Hypercalcaemia in a Patient on Lithium Therapy: A Case Report.

F M Tanvir Alam, Zarin Tasnim Parisa, Francis Donya, Anurag Sharma

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

F M Tanvir AlamInternal Medicine, Medway NHS Foundation Trust, Kent, GBR.
Zarin Tasnim ParisaInternal Medicine, Medway NHS Foundation Trust, Kent, GBR.
Francis DonyaInternal Medicine, Medway NHS Foundation Trust, Kent, GBR.
Anurag SharmaGeriatrics, William Harvey Hospital in Ashford, Ashford, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lithium is a commonly used drug in the treatment of several psychiatric disorders. However, due to its narrow therapeutic range, vigilant monitoring is essential to detect adverse effects. While hypercalcaemia is a documented complication of lithium therapy, it is typically associated with hyperparathyroidism. This case report presents a 67-year-old female on prolonged lithium therapy who developed refractory hypercalcaemia that was not attributable to hyperparathyroidism. Discontinuation of lithium resulted in normalisation of calcium levels, confirming lithium-induced hypercalcaemia in the context of normal parathyroid hormone (PTH) levels. The existing literature predominantly discusses hypercalcaemia as a consequence of hyperparathyroidism in lithium users. This case challenges that paradigm, suggesting an alternative, as yet undefined, mechanism for lithium-induced hypercalcaemia.

Indexed as

bipolar affective disorderhypercalcaemialithium-induced hypercalcemiamood stabilizernon-hyperparathyroid

Identifiers

PMID41185877
PMCPMC12579908

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.