ArticleOncoTargets and therapy2025
Real-World Experience of Niraparib as Maintenance Therapy in Patients with Newly Diagnosed Advanced Ovarian Cancer: A Single-Center Retrospective Study.
Article in OncoTargets and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Combinational therapy of cervical cancer consisting of probiotic particles and vincristine: a molecular in vitro study.Medical oncology (Northwood, London, England) · 2025Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to evaluate the efficacy and safety of niraparib as a maintenance treatment for newly diagnosed advanced ovarian cancer in a real-world setting. Methods: This retrospective observational study included patients with histologically confirmed epithelial ovarian cancer, primary peritoneal or fallopian tube cancer who received niraparib as first-line maintenance therapy at Tianjin Cancer Hospital between January 2021 and January 2023. Clinicopathological characteristics and treatment outcomes were extracted from medical records. The efficacy of niraparib was evaluated by progression-free survival (PFS), and safety was assessed using the Common Terminology Criteria for Adverse Events (CTCAE) version 5.0. Results: A total of 102 patients were enrolled in this study. After a median follow-up of 21.4 months (IQR 20.4-22.5 months), the median PFS was 25.7 months in the overall population, not reached in the Conclusion: In the real-world setting, the use of niraparib as a maintenance treatment for newly diagnosed advanced ovarian cancer has been shown to be effective and well tolerated, which is consistent with the results of previous randomized Phase III trials.
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