Evidence map›Paper›PMID 41185838›Full record

ArticleCureus2025

Marjolin Ulcer: Squamous Cell Carcinoma Arising in a Modeling Agent-Induced Ulcer.

Naomi H Domínguez-Wakida, Azyadeth Gracián-Castro, Marcela Hernández-Vera, Ilse Y Osorio-Aragón, Elisa Vega-Memije

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Naomi H Domínguez-WakidaDermatology, Hospital General "Dr. Manuel Gea González", Mexico City, MEX.
Azyadeth Gracián-CastroDermatology, Hospital General "Dr. Manuel Gea González", Mexico City, MEX.
Marcela Hernández-VeraDermatology, Hospital General "Dr. Manuel Gea González", Mexico City, MEX.
Ilse Y Osorio-AragónDermatopathology, Hospital General "Dr. Manuel Gea González", Mexico City, MEX.
Elisa Vega-MemijeDermatology, Hospital General "Dr. Manuel Gea González", Mexico City, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of modeling substances, such as mineral oil, can trigger chronic inflammatory reactions with serious complications, including persistent ulceration. In rare cases, these lesions may undergo malignant transformation to aggressive cutaneous neoplasms, such as Marjolin ulcers. We present the case of a 55-year-old transgender woman with a history of mineral oil injection who developed a chronic leg ulcer that underwent malignant transformation, with histological confirmation of a well-differentiated squamous cell carcinoma. This case highlights the importance of close monitoring of chronic ulcers in this patient population and underscores the severe consequences of using unregulated modeling agents.

Indexed as

malignant transformationmarjolin ulcermineral oilmodeling agent reactionssquamous cell carcinoma

Identifiers

PMID41185838
PMCPMC12579590

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.