ArticleCureus2025
Clear but Not Simple: Diagnostic Challenges of a Rare Case of Hyalinising Clear Cell Carcinoma of the Palate.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Salivary Hyalinizing Clear Cell Carcinoma and Odontogenic Clear Cell Carcinoma: A Case Series and a Scoping Review Comparing Clinicopathological Presentations.Diagnostics (Basel, Switzerland) · 2026Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyalinising clear cell carcinoma is an uncommon neoplasm arising in minor salivary glands. It is a rare low-grade malignant tumour composed of clear cytoplasmic cells. This case report outlines the presentation of a 36-year-old female with a history of growth in the palatal region for six months. Examination revealed a mass originating from the left hard palatal region, and on correlation with radiographic examination, biopsy was advised. Pathological examination revealed typical clear cells arranged in anastomosing trabeculae, cords, nests, or solid sheets with hyalinising stroma. These cells were strongly positive for periodic acid-Schiff (PAS) but were negative for mucicarmine. Immunohistochemically, these neoplastic cells were immunoreactive to cytokeratin 8/18 but negative to smooth muscle actin, which aids in the diagnosis. Left subtotal maxillectomy was done for the excision of the tumour, followed by radiotherapy, along with follow-up of 18 months without recurrence.
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