ArticleCureus2025
A Creative Solution for a Difficult Case: Endoluminal Negative Pressure Therapy for the Management of Colorectal Anastomotic Leak.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rectal anastomotic leaks can lead to significant morbidity with potentially devastating consequences for patients' intestinal continuity and quality of life, which are challenging to manage. With a growing interest in endoluminal negative pressure therapy (eNPT), which was first described for use in esophageal anastomotic leaks, the technique has been more recently adapted to colorectal anastomoses. We discuss a case of a patient with rectal cancer, who underwent total neoadjuvant therapy, ultralow anterior resection, and diverting loop ileostomy. The patient suffered an anastomotic leak and presacral abscess. Attempts at conventional management to control pelvic sepsis were unsuccessful. We present the novel creation of an eNPT device (a manufactured one is not readily available in Canada), which allowed control of sepsis, substantial reduction in abscess size, and safe discharge home for the patient. This experience suggests this is a safe and feasible treatment alternative for this challenging problem.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.