ArticleCureus2025
Effect of Bupivacaine-Soaked Polypropylene Mesh on Postoperative Pain in Patients Undergoing Lichtenstein Repair for Inguinal Hernia.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
backgroundInguinal hernia repair is among the most common general surgical procedures worldwide, with the Lichtenstein tension-free mesh repair regarded as the gold standard due to its low recurrence rates and favorable outcomes. However, postoperative pain remains a significant concern. The use of bupivacaine-soaked mesh has been proposed as a technique to enhance analgesia and facilitate faster recovery.
objectivesThis study aimed to evaluate the efficacy of 0.5% bupivacaine-soaked polypropylene mesh in reducing postoperative pain and hospital stay in patients undergoing Lichtenstein repair for unilateral inguinal hernia.
methodsA prospective cohort study was conducted over 18 months in a tertiary care teaching hospital in Northern India, involving 86 adult patients undergoing elective unilateral inguinal hernia repair. Participants were divided into Group A (bupivacaine-soaked mesh) and Group B (non-soaked mesh). Pain was assessed using the Visual Analogue Scale (VAS) at six, 12, and 24 hours postoperatively. Additional analgesic requirements and hospital stay duration were also recorded. Statistical analysis was performed using IBM SPSS Statistics for Windows, version 24.0 (IBM Corp., Armonk, New York, United States).
resultsBoth groups were comparable in baseline characteristics. Group A showed significantly lower VAS scores at six hours (3.95 ± 0.53 vs 4.53 ± 0.68), 12 hours (3.56 ± 0.50 vs 4.09 ± 0.8), and 24 hours (1.65 ± 0.48 vs 2.32 ± 0.52) (p < 0.05). Diclofenac requirement was significantly lower in Group A (p = 0.0004), and 67.4% were discharged by day 3 compared to 4.7% in Group B (p < 0.0001).
conclusionThe use of 0.5% bupivacaine-soaked mesh in Lichtenstein repair significantly reduces postoperative pain and shortens hospital stay, supporting its role as an effective adjunct in inguinal hernia surgery.
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