ArticleCureus2025
Chromosomal Abnormalities in Recurrent Pregnancy Loss at a Tertiary Care Center.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- The role of satellite DNA-enriched heterochromatic variants in reproductive disorders: Insights from standardized cytogenetic analysis.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026Article
- Article
- Immunotherapy and IVF Outcomes in Unexplained Recurrent Pregnancy Loss: A Systematic Review with Implications for Personalized Reproductive Medicine.Journal of personalized medicine · 2025Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStructural and numerical variation in chromosomes in couples leads to recurrent pregnancy loss/abortions, which disrupts the normal embryonic development. This study aimed to evaluate the incidence of chromosomal abnormalities in couples experiencing recurrent abortions. MATERIALS AND
methodsThirty couples (N = 60) experiencing one or more abortions were enrolled. Couples experiencing one abortion were also included because of having suspicion of abnormality by the clinician. These couples were categorized as follows: couples with recurrent abortion and couples with recurrent abortion preceded by stillbirth or abnormal child (opted abortion). These cases were investigated by using G-banding karyotyping.
resultIn our study, heteromorphism of chromosome 9 was a ubiquitous finding in couples having recurrent abortions. In affected individuals/couples with chromosomal abnormalities in recurrent abortion cases, the female-to-male ratio was 5:2.
conclusionsChromosomal analysis is an important investigation for couples experiencing recurrent abortions. Heteromorphism of chromosome 9 is also an important finding in recurrent abortion. Genetic investigation, including karyotyping, would help in genetic counseling as well as decision-making and exploring further reproductive options.
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Registered trials
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