ArticleCureus2025
Minocycline-Induced Angioedema With Chronic Recurrent Urticaria Even After Drug Withdrawal: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Minocycline is a tetracycline antibiotic widely prescribed for several conditions, including acne, rosacea, and chlamydial and staphylococcal infections. Although cutaneous adverse reactions are known, severe immediate hypersensitivity requiring intensive care is rare. Even less common is prolonged urticaria persisting after drug discontinuation. A 16-year-old female patient developed diffuse urticaria and angioedema requiring intensive care within four days of minocycline initiation. Despite discontinuation and acute management, recurrent urticarial episodes occurred for over 12 months without re-exposure, requiring intermittent corticosteroid treatment. Causality assessment using the Naranjo Adverse Drug Reaction Probability Scale (score 7) indicated a probable association between minocycline and the observed reaction. This report highlights an uncommon clinical course of minocycline-induced angioedema with chronic recurrent urticaria persisting long after drug withdrawal.
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