Evidence map›Paper›PMID 41185760›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2025

Brillouin Metrics of the Crystalline Lens Comparison Between Low-Medium Myopia and High Myopia.

Yongle Bao, Yong Ma, Jian Cao, Yanze Yu, Teruko Fukuyama, Zhe Zhang, Lingling Niu, Peijun Yao, Xiaoying Wang, Xingtao Zhou and 1 more

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Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Yongle Bao *Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China.
Yong Ma *Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China.
Jian Cao *State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, People's Republic of China.
Yanze YuDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China.
Teruko FukuyamaDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China.
Zhe ZhangDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China.
Lingling NiuDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China.ORCID 0009-0001-2316-1099
Peijun YaoDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China.
Xiaoying WangDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China.
Xingtao ZhouDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China.ORCID 0000-0002-3465-1579
Jing ZhaoDepartment of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the impact of myopia on the Brillouin biomechanics and morphology of crystalline lenses in Chinese adults. Methods: Patients with myopia were enrolled and divided into low-medium (spherical equivalent [SE] ≥ -5.75 D, N = 66) and high (SE ≤ -6.0 D, N = 72) myopia groups. All patients underwent routine ophthalmic examinations, including SE, axial length, and anterior chamber metrics (Pentacam) measurements. The Brillouin-related metrics of the crystalline lenses were measured using a Brillouin microscopy. The morphological parameters included the Width of Top Plateau (WTP), Width of Bottom Plateau (WBP), Bottom-Top (B-T), Slope of Anterior Cortex (SAC), and Slope of Posterior Cortex (SPC). The height of Plateau was a biomechanical parameter. Results: The study included 138 eyes (138 patients); the mean age was 28.43 ± 8.31 years. WBP, B-T, SAC, and SPC significantly differed between the high and low-medium myopia groups (all Conclusion: An increase in the degree of myopia could be associated with posterior cortex thickening while maintaining stable biomechanics and morphology of the crystalline lens nucleus. Brillouin microscopy can serve as an effective technique for multidisciplinary lens biomechanical and morphological imaging.

Indexed as

biomechanicsBrillouin microscopycrystalline lensmorphologymyopia

Identifiers

PMID41185760
PMCPMC12579875

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