ReviewJournal of pain research2025
New Findings on Risk Factors for Postherpetic Neuralgia From 2014 to 2024: A Systematic Review and Meta-Analysis.
Review in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Current advances in the epidemiology, risk factors, prevention, management, and long-term outcomes of herpes zoster and post-herpetic neuralgia.Frontiers in microbiology · 2026Pooled it
- Risk prediction models for postherpetic neuralgia: a systematic review and meta-analysis.Frontiers in neurologyPooled it
- Efficacy of Ultrasound-Guided Intercostal Nerve Block With Liposomal Bupivacaine for Treating Postherpetic Neuralgia in Adult Patients.The Kaohsiung journal of medical sciences · 2026Article
- Predictive Value of Anxiety State During Acute Herpes Zoster for the Development of Postherpetic Neuralgia.Actas espanolas de psiquiatria · 2026Article
- Unraveling immune-inflammation-aging network interactions: an interpretable machine learning model predicts the risk of postherpetic neuralgia.Frontiers in immunology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Postherpetic neuralgia (PHN) is a significant public health issue that severely impacts patients' quality of life. This systematic review is the first to conduct a meta-analysis of newly identified risk factors for PHN over the past decade, evaluating the temporal changes in these risk factors to assist clinicians in predicting the occurrence of PHN. Methods: Cohort and case-control studies on PHN risk factors were retrieved from PubMed, Web of Science, Embase and Cochrane Library (January 1, 2014-March 26, 2024). Study quality was assessed using the Agency for Healthcare Research and Quality (AHRQ) or the Newcastle-Ottawa Scale (NOS). Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to assess risk factor effects. Results: Seventeen studies involving 124,078 participants were included, identifying 81 potential risk factors. Eleven factors were meta-analyzed, and significant risk factors among these included age (age 60-69 (OR=2.05, 95% CI=[1.92,2.19], Conclusion: COPD, hypertension, anxiety/depression, malignancy and peptic ulcers may represent newly identified PHN risk factors. Given the limitations of the research, the results should be interpreted with caution. Future research should focus on these factors to enhance clinical prediction and prevention strategies. Trial Registration: This study is registered in the PROSPERO database (No. CRD42024543589).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.