Evidence map›Paper›PMID 41185614›Full record

ArticleGeobiology

A Comprehensive Study of Biohopanoid Production in Alphaproteobacteria: Biosynthetic, Chemotaxonomical, and Geobiological Implications.

Jaap S Sinninghe Damsté, Michel Koenen, Vera Thiel, Nora Richter, Ellen C Hopmans, Nicole J Bale

Abstract read
In one paragraph

Article in Geobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jaap S Sinninghe DamstéDepartment of Marine Microbiology and Biogeochemistry, NIOZ Royal Institute for Sea Research, Texel, the Netherlands.ORCID 0000-0002-8683-1854
Michel KoenenDepartment of Marine Microbiology and Biogeochemistry, NIOZ Royal Institute for Sea Research, Texel, the Netherlands.ORCID 0000-0002-8398-6500
Vera ThielDepartment of Microorganisms, Leibniz-Institute DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen, Braunschweig, Germany.ORCID 0000-0003-2833-8911
Nora RichterDepartment of Marine Microbiology and Biogeochemistry, NIOZ Royal Institute for Sea Research, Texel, the Netherlands.ORCID 0000-0002-4613-005X
Ellen C HopmansDepartment of Marine Microbiology and Biogeochemistry, NIOZ Royal Institute for Sea Research, Texel, the Netherlands.ORCID 0000-0002-8209-1334
Nicole J BaleDepartment of Marine Microbiology and Biogeochemistry, NIOZ Royal Institute for Sea Research, Texel, the Netherlands.ORCID 0000-0001-9118-3890

Funding

European Research Council 694569Soehngen Institute for Anaerobic Microbiology 024.002.002
6 · The paper itself

Abstract

Bacteriohopanepolyol derivatives (BHPDs) and dia- and catagenetic products formed from these bacterial membrane modifiers are extensively used as biomarkers in molecular ecological and geoscience studies. Some BHPDs can be assigned to specific phylogenetic bacterial groups. With the vastly increasing availability of complete bacterial genomes, hopanoid production can be readily predicted by the presence of specific genes encoding biosynthetic enzymes involved in their production, but the time-consuming physiological confirmation remains a critical element in the interpretation of such data in a biosynthetic and paleontological context. Alphaproteobacteria (APB) have often been proposed as important BHPD producers in a wide variety of environments and produce indicative BHPDs containing an additional methyl group in the A-ring, complicating the assignment of 2-methyl hopanes to N

Indexed as

AlphaproteobacteriaTriterpenesGenotypePhylogenyTriterpenes2‐methyl hopane indexbacteriohopanepolyol derivativesbiosynthesisbiosynthetic gene clustershopanoidsmethylated hopanoidstetrahymanol

Identifiers

PMID41185614
PMCPMC12583986

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.