Evidence map›Paper›PMID 41185103›Full record

ArticlePsycho-oncology2025

Establishing the Ecological Validity of Cognitive Patient Reported Outcome Measures in Breast Cancer Survivors: A Prospective Cohort Study.

Ashley M Henneghan, Oscar Y Franco-Rocha, Kathleen M Van Dyk, Emily W Paolillo, Darren Haywood, Raeanne C Moore

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ashley M HenneghanSchool of Nursing, University of Texas at Austin, Austin, Texas, USA.ORCID 0000-0002-6733-1926
Oscar Y Franco-RochaSchool of Nursing, University of Texas at Austin, Austin, Texas, USA.ORCID 0000-0002-5547-1518
Kathleen M Van DykSemel Institute of Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0003-1500-930X
Emily W PaolilloDepartment of Neurology, Memory and Aging Center, University of California, San Francisco, Weill Institute for Neurosciences, San Francisco, California, USA.
Darren HaywoodHuman Performance Research Centre, INSIGHT Research Institute, Faculty of Health, University of Technology Sydney (UTS), Sydney, Australia.ORCID 0000-0002-9317-4135
Raeanne C MooreDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.

Funding

Social Determinants of Health as Transducers of Cellular Aging: A New Multi-level Paradigm to Reduce Survivorship Disparities at the Intersection of Cancer and AgingR35CA283926 · NCI · GEORGETOWN UNIVERSITY · PI Jeanne Mandelblatt · 2023 to 2026
$3.7M
Precision Health Intervention Methodology Training in Self-Management of Multiple Chronic ConditionsT32NR019035 · NINR · UNIVERSITY OF TEXAS AT AUSTIN · PI STUIFBERGEN, ALEXA · 2020 to 2024
$995k
Brain Health in Breast Cancer Survivors: Interaction of Menopause and Endocrine TherapyK08CA241337 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VAN DYK, KATHLEEN · 2019 to 2023
$925k
Defining Cognitive Patient Reported Outcomes of Breast Cancer Survivors in the Context of Everyday Functioning and Quality of LifeR21NR020497 · NINR · UNIVERSITY OF TEXAS AT AUSTIN · PI HENNEGHAN, ASHLEY M. · 2023 to 2024
$447k
NCI NIH HHS K08 CA241337NCI NIH HHS R35 CA283926NIH HHS K08CA241337NIH HHS R21NR020497NIH HHS R35CA283926NINR NIH HHS R21 NR020497NINR NIH HHS T32 NR019035
6 · The paper itself

Abstract

objectiveThe aim of this study was to determine which cognitive patient reported outcome measure (PROM) best represents self-reported cognitive functioning in real-world environments among breast cancer survivors (BCS) as measured by ecological momentary assessments (EMA), and to compare their ability to predict future everyday functioning.

methodsOne-hundred twenty-four BCS (ages 24-88) completed self-report measures of cognitive functioning (FACT-Cog PCI, PROMIS Cog, CFQ, EORTC-CF) and everyday functioning (SDI, FACT-G Functional Well-being subscale) at baseline (Time 1) and at 9 weeks follow up (Time 2). Between assessments, EMA protocols (including one item to assess cancer-related cognitive symptoms) were administered every other day for 8 weeks. Person-specific means and standard deviations were calculated for EMA data. Hierarchical linear regression models were used to model cognitive PROM predictors of person-specific averages and variability in EMAs, SDI, and FACT-G functional well-being, and model parameters (R

resultsFollow-up FACT-Cog PCI most accurately predicted both the average (ΔR

conclusionsThese findings support the ecological validity of cognitive PROMs in BCS and indicate that both FACT-Cog PCI and PROMIS Cog effectively capture real-world cognitive symptoms and predict future everyday functioning, including social function and well-being.

Indexed as

Breast NeoplasmsCancer SurvivorsCognitionEcological Momentary AssessmentPatient Reported Outcome MeasuresActivities of Daily LivingAdultAgedAged, 80 and overFemaleHumansMiddle AgedProspective StudiesQuality of LifeReproducibility of ResultsSelf Reportbreast cancercancercancer‐related cognitive impairmentecological momentary assessmenteveryday functioningoncologypatient reported outcome measureself‐report

Identifiers

PMID41185103
PMCPMC12583681

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.