Evidence map›Paper›PMID 41185067›Full record

ArticleBMC research notes2025

Clinical characteristics and treatment outcomes of pediatric achalasia: a 10-year experience from a tertiary center in Iran.

Abtin Mazhari, Hosein Alimadadi, Behdad Gharib, Sara Memarian

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Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Abtin MazhariSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Hosein AlimadadiChildren's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Behdad GharibChildren's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Sara MemarianChildren's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. sara.memarian64@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to examine demographic patterns, clinical presentation, diagnostic methods, and therapeutic outcomes of achalasia patients in a tertiary hospital in Tehran, Iran. We conducted a retrospective study of patients aged < 18 years with a diagnosis confirmed by barium swallow and endoscopy; those with other diagnoses or incomplete data were excluded.

resultsWe included 100 patients (59 boys, 41 girls; mean age: 7.45 ± 4.58 years, range: 4 months - 16 years) diagnosed between 2013 and 2022. The most common symptoms were dysphagia (83%), nausea/vomiting (78%), and weight loss (49%). The mean diagnostic delay was 22.04 ± 32.75 months. Comorbid conditions were present in 23% of the patients, most commonly esophageal atresia and Allgrove syndrome. The classic bird's beak sign was seen in 61% of the barium images. 95% of the patients went through pneumatic dilatation (PD), and a successful response to PD was defined as clinical improvement and resolution of dysphagia. 31.6% of them responded to a single PD session, while 68.4% required multiple PD sessions or Heller myotomy. Younger age was significantly associated with the need for multiple PD sessions (p = 0.001). No major complication was seen.

Indexed as

Esophageal AchalasiaTertiary Care CentersAdolescentChildChild, PreschoolDeglutition DisordersDilatationFemaleHumansInfantIranMaleRetrospective StudiesTreatment OutcomeAchalasiaChildrenHeller myotomyPneumatic dilatation

Identifiers

PMID41185067
PMCPMC12581397

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