Evidence map›Paper›PMID 41184950›Full record

ArticleSystematic reviews2025

Surgical compared to percutaneous repair of aortic coarctation in the pediatric population: a protocol for a systematic review and meta-analysis update.

Valentina Pérez-Ariza, María Paula Delgado-Pérez, Silvia Alejandra Prada, Javier Maldonado-Escalante, Kevin Maldonado-Cañón

Abstract read
In one paragraph

Article in Systematic reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Valentina Pérez-ArizaSchool of Medicine, Universidad de los Andes, Bogota, Colombia. v.pereza@uniandes.edu.co.ORCID 0000-0002-2031-730X
María Paula Delgado-PérezSchool of Medicine, Universidad de los Andes, Bogota, Colombia.
Silvia Alejandra PradaGrupo de Investigación en Cirugía Cardiovascular, Department of Surgery, Clínica Universitaria Colombia, Bogotá, Colombia.
Javier Maldonado-EscalanteSchool of Medicine, Universidad de los Andes, Bogota, Colombia.
Kevin Maldonado-CañónGrupo de Investigación en Cirugía Cardiovascular, Department of Surgery, Clínica Universitaria Colombia, Bogotá, Colombia.ORCID 0000-0003-1649-5290

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNative coarctation of the aorta (CoA) accounts for 6-8% of congenital heart defects and poses significant morbidity and mortality risks if untreated. By incorporating the most recent evidence, focusing on the pediatric population, this protocol outlines the planned approach for a systematic review and meta-analysis update that will compare the long-term safety and effectiveness of surgical repair, balloon angioplasty, and stenting in CoA patients.

methodsFollowing PRISMA guidelines, a systematic review and meta-analysis will be conducted. Electronic databases, including Scopus, LILACS, MEDLINE, CENTRAL, EMBASE, IBECS, OpenGrey, and major trial registries, will be searched for comparative studies of stent versus surgery and of balloon angioplasty versus surgery. Randomized control trials and observational studies focused on pediatric patients will be eligible. Two independent reviewers will screen the titles and abstracts based on predefined eligibility criteria, and two will assess the full texts of relevant studies. Quality assessment will be done with the Cochrane Risk of Bias tool for RCTs and the Newcastle-Ottawa Scale for observational studies. Pre-planned analyses, including quantitative and sensitivity analyses, are detailed within this protocol. R Studio will be used to analyze the data. The strength of the body of evidence will be assessed using GRADE. DISCUSSION: Despite recent advances in surgical and percutaneous techniques for CoA, there remains uncertainty on the best strategy for achieving long-term safety and effectiveness of treatment, particularly in the pediatric population. This study's comprehensive comparative outcomes analysis will help bridge these gaps and inform clinical decision-making. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42024549170. Registered on May 20th 2024.

Indexed as

Angioplasty, BalloonAortic CoarctationChildHumansMeta-Analysis as TopicResearch DesignStentsSystematic Reviews as TopicAortic coarctationBalloon angioplastyCardiovascular surgeryPediatricStent

Identifiers

PMID41184950
PMCPMC12581518

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.