Evidence map›Paper›PMID 41184930›Full record

ArticleScandinavian journal of trauma, resuscitation and emergency medicine2025

Successful prehospital extracorporeal cardiopulmonary resuscitation in pediatric cardiac arrest - a case report.

Martin Breitkopf, Christoph Wihler, Andreas Walther, Daniel Räpple, Gunter Kerst, Johannes Heymer, Matthias Ott

Abstract readCase Reports
In one paragraph

Article in Scandinavian journal of trauma, resuscitation and emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Martin BreitkopfDepartment of Anesthesiology, Klinikum Stuttgart, Stuttgart, Germany. m.breitkopf@klinikum-stuttgart.de.
Christoph WihlerDepartment of Anesthesiology, Klinikum Stuttgart, Stuttgart, Germany.
Andreas WaltherDepartment of Anesthesiology, Klinikum Stuttgart, Stuttgart, Germany.
Daniel RäppleInternal Intensive Care Medicine, Klinikum Stuttgart, Stuttgart, Germany.
Gunter KerstCenter for Congenital Heart Defects Stuttgart, Pediatric Intensive Care, Pulmonology and Allergology, Klinikum Stuttgart, Stuttgart, Germany.
Johannes HeymerInternal Intensive Care Medicine, Klinikum Stuttgart, Stuttgart, Germany.
Matthias OttInternal Intensive Care Medicine, Klinikum Stuttgart, Stuttgart, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCardiac arrest in children necessitates a systematic approach, including Basic Life Support, Advanced Life Support and post-resuscitation care. Extracorporeal Cardiopulmonary Resuscitation offers a viable option for refractory cardiac arrest by providing hemodynamic support through extracorporeal circulation. While prehospital E-CPR in pediatric patients remains rare, two cases were reported in the Netherlands in 2023, demonstrating feasibility despite poor outcomes. We present the first documented case of pediatric prehospital E-CPR in Germany, conducted as part of the Klinikum Stuttgart extracorporeal membrane oxygenation program, showcasing its implementation in an urban setting. CASE PRESENTATION: A 16-year-old patient with known hypertrophic non-obstructive cardiomyopathy suffered a cardiac arrest following exertion. After unsuccessful conventional resuscitation, prehospital ECMO cannulation was initiated. Cannulation was performed without complications (15 French (23 cm arterial, 25 Fr 55 cm venous), achieving a flow rate of 4500 mL/min and stable hemodynamics. Echocardiography revealed a significantly thickened septal wall and impaired ejection function. During transport under ECMO support, spontaneous movements and breathing were observed, managed with sedation and lung-protective ventilation. OUTCOME: Upon hospital admission, whole-body CT revealed only free intraperitoneal fluid consistent with anasarca, without vascular or cannulation-related complications. The patient was weaned from ECMO and extubated after 48 h, developing transient mild delirium and aspiration pneumonia, both resolved. An ICD was implanted for secondary prevention, and the patient was discharged neurologically intact (cerebral performance category 1).

conclusionGiven the limited availability of pediatric E-CPR and the challenges of long transport distances, structured prehospital E-CPR programs with specialized teams may provide a viable solution for critically ill pediatric patients.

Indexed as

Cardiopulmonary ResuscitationEmergency Medical ServicesExtracorporeal Membrane OxygenationOut-of-Hospital Cardiac ArrestAdolescentHumansCardiac arrestExtracorporeal cardiopulmonary resuscitationExtracorporeal membrane oxygenationPediatricPrehospital

Identifiers

PMID41184930
PMCPMC12581532

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.