Evidence map›Paper›PMID 41184905›Full record

ArticleTrials2025

Action observation therapy effects on motor function and balance in cerebral palsy: an fNIRS-based randomized trial.

Melike Özipek, Mevhibe Saricaoglu, Lütfü Hanoğlu, Fatma Mutluay

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05995197 (The Effect of Action Observation Therapy on Balance in Patients With Cerebral Palsy), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05995197 naunknown statusnot on this map

The Effect of Action Observation Therapy on Balance in Patients With Cerebral Palsy

TypeinterventionalSponsorMedipol UniversityRan2023 to 2025Enrolled24ConditionsCerebral Palsy, Exercise TherapyArmsaction observation
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Melike ÖzipekInstitute of Health Sciences, Istanbul Medipol University, Istanbul, Turkey. melikesen67@hotmail.com.ORCID http://orcid.org/0000-0002-8921-0922
Mevhibe SaricaogluVocational School, Program of Electroneurophysiology, Istanbul Medipol University, Istanbul, Turkey.
Lütfü HanoğluResearch Institute for Health Sciences and Technologies (SABITA), Regenerative and Restorative Medicine Research Center (REMER), Clinical Electrophysiology, Neuroimaging and Neuromodulation Lab, Istanbul Medipol University, Istanbul, Turkey.
Fatma MutluayDepartment of Physiotherapy and Rehabilitation, Yalova University Faculty of Health Sciences, Yalova, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral palsy (CP) is an umbrella term for movement, motor, and posture disorders that occur in the developing brain from any non-progressive cause. Action observation therapy (AOT) is a method used in the treatment of motor disorders. Here, the manuscript presents the study protocol for the effect of AOT on balance using functional near-infrared spectroscopy (fNIRS). This study protocol aims to comprehensively evaluate the impact of AOT in patients with CP regarding brain activation and behavioral and motor symptoms. This is a single-center randomized controlled trial for patients with CP. Patients determined eligible according to the study criteria will be randomized into two treatment groups: the action observation therapy group and the control group. Each group will include 12 patients, and the age range is 5-15. The patients will be treated for 15 sessions for three consecutive weeks. In this study, AOT will be applied to improve balance. The following tests will be applied to evaluate the patients' motor function and balance skills before rehabilitation. Gross Motor Function Measure-88 (GMFM-88)-D and E parts, Lower Extremity Selective Control Evaluation Scale (SCALE), The Trunk Impairment Scale (TIS), Pediatric Balance Scale, Nintendo Wii-Fit Balance Score, Timed Up and Go Test (TUG), and Pediatric Data Collection Tool (PODCI) will be applied. Brain regional blood flow changes during static and dynamic balance will be evaluated with fNIRS. All evaluations will be performed before treatment and repeated after treatment.Trial registrations Study was approved by the Istanbul Medipol University Non-Interventional Clinical Research Ethics Committee (Ethical Report No: E-10840098-772.02-3957), registered at ClinicalTrials.gov with the number NCT05995197, 08.09.2023.

Indexed as

BrainCerebral PalsyMotor ActivityPostural BalanceAdolescentChildChild, PreschoolFemaleHumansMaleMotor SkillsRandomized Controlled Trials as TopicRecovery of FunctionSpectroscopy, Near-InfraredTime FactorsTreatment OutcomeAction observation therapyBalanceCerebral palsyFNIRS

Identifiers

PMID41184905
PMCPMC12581447

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.