ArticleBMC public health2025
Higher Life's Essential 8 score is associated with lower risk of kidney stones in Chinese adults: a cross-sectional study.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
Abstract
backgroundKidney stones are widely prevalent throughout the world and impose a significant economic and medical burden on individuals and society. The aim of this study was to analyze the association between Life's Essential 8 (LE8) score and kidney stones, to provide more precise interventions for the prevention of kidney stones.
methodsThis was a cross-sectional study that used baseline survey data from the Chinese Multi-Ethnic Cohort (CMEC) with 93,297 eligible participants. Participants' LE8 score was measured according to the American Heart Association definition. Abdominal ultrasonography was used for the diagnosis of kidney stones. Logistics regression models and restricted cubic spline regression models were used to explore the association between LE8 and its subscale scores and the risk of kidney stones. Subgroup analyses were used to further explore the specific effects of increasing LE8 score on kidney stones in populations with different characteristics.
resultsIn this study, a total of 6,327 subjects (6.78%) had kidney stones. Fully adjusted multifactorial logistic regression showed that CVH levels were significantly and negatively correlated with the risk of kidney stones (moderate CVH: OR = 0.76, 95% CI: 0.70-0.82; high CVH: OR = 0.62, 95% CI: 0.56-0.69). Restricted cubic spline regression analysis showed a linear inverse dose-response relationship between both LE8 and its subscale scores and the risk of kidney stones. In addition, subgroup analyses further showed that the negative association between LE8 score and kidney stones risk was more pronounced in males, frequent tea drinkers, and those with higher levels of education.
conclusionsHigher LE8 and its subscale scores were associated with a lower risk of kidney stones. Adherence to a more optimal CVH will likely be a comprehensive preventive and management measure to reduce the severe disease burden of kidney stones.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.