ArticleBMC pediatrics2025
Laparoscopic-assisted transanal soave for refractory constipation in children: outcomes and management.
Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study evaluates the efficacy and safety of laparoscopic-assisted transanal Soave procedure (LATSP) in children with refractory constipation unrelated to Hirschsprung's disease, addressing the paucity of evidence for surgical management in this population.
methodsA single-center retrospective cohort of 30 children (median age: 4 years; range: 1-13) underwent LATSP after failing ≥ 6 months of standardized conservative therapy (dual laxatives + biofeedback). Preoperative evaluation excluded structural/neurogenic etiologies via MRI, barium enema, anorectal manometry, and rectal biopsy confirming the presence of ganglion cells. Primary outcomes included Symptom Severity (SS) scores (0-65) and Bristol Stool Form Scale (BSFS) at 6/24/36 months postoperatively. Complications were graded by Clavien-Dindo.
resultsSS scores decreased from 29.1 ± 9.1 preoperatively to 9.2 ± 3.3 at 36 months (P < 0.001). Stool normalization (BSFS Types 4-5) increased from 10% to 73.4% (P < 0.001). Four complications occurred (13.3%): fecal incontinence (n = 2, Grade II), anal bleeding (n = 1, Grade I), and presacral infection (n = 1, Grade IIIb), all resolved without sequelae. LATSP showed superior symptom resolution versus historical Malone ACE cohorts (73.4% vs. 20% at 6 years).
conclusionsLATSP is a safe and effective intervention for carefully selected children with refractory constipation, providing sustained symptom relief without permanent stomas. Multidisciplinary postoperative protocols are essential for optimal outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.