Evidence map›Paper›PMID 41184750›Full record

ArticleBMC gastroenterology2025

A novel model of dual-network composite hydrogels for application in endoscopic submucosal dissection.

Fei Zhao, YunFang Bai, JunJie Wu, ZhiHao Zhu, JinLei Mao, Aikebaier Aili, HongRun Gu, ShiJie Yu, ZhiFei Wang

Abstract read
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fei ZhaoDepartment of Clinical Medicine, Medical College of Soochow University, Suzhou, People's Republic of China.
YunFang BaiGeneral Surgery, Cancer Center, Department of Hernia Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
JunJie WuGeneral Surgery, Cancer Center, Department of Hernia Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
ZhiHao ZhuGeneral Surgery, Cancer Center, Department of Hernia Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
JinLei MaoGeneral Surgery, Cancer Center, Department of Hernia Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Aikebaier AiliDepartment of Minimally Invasive Surgery, Hernias and Abdominal Wall Surgery, Xinjiang Clinical Research Center for Gastroesophageal Reflux Disease and Bariatric Metabolic Surgery, Research Institute of General and Minimally Invasive Surgery, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang Uygur Autonomous Region, 830002, China.
HongRun GuGeneral Surgery, Cancer Center, Department of Hernia Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
ShiJie YuGeneral Surgery, Cancer Center, Department of Hernia Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China. Yusj19981120@163.com.
ZhiFei WangGeneral Surgery, Cancer Center, Department of Hernia Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China. wangzhifei1973@zju.edu.cn.

Funding

the fund program: General Scientific Research project of Zhejiang Provincial Health Commission 2024KY699the General Research Project of the Zhejiang Provincial Department of Education Y202249352the Subproject of the Xinjiang Uygur Autonomous Region Regional Cooperative Innovation Program 20222101517
6 · The paper itself

Abstract

BACKGROUND AND

aimsEndoscopic submucosal dissection (ESD) is a critical technique for treating early-stage gastrointestinal tumors, requiring precise operational skills. Traditional training methods, however, face challenges such as high costs, ethical concerns, and sustainability issues. This study aims to design a novel training model based on dual-network composite hydrogel (DNH) (Jing, et al, Polymers 11:952,2019) to simulate the multilayered structure of gastric tissue, providing a more realistic and effective training environment.

methodsA new DNH model was developed to simulate gastric tissue's structure and biomechanics. The effectiveness of the model in ESD training was evaluated through structured assessments with participants of different experience levels. Physicians trained with the DNH model were evaluated for technical precision, efficiency, and complication risk.

resultsThe DNH model demonstrated superior performance, with physicians using the model showing significantly higher technical precision and efficiency in ESD procedures. Additionally, the model resulted in a substantially reduced risk of complications compared to traditional methods. Participants rated the model highly for reusability and lower cost, confirming its effectiveness as a training tool.

conclusionsThe dual-network composite hydrogel model offers great potential for ESD training, providing an efficient, safe, and cost-effective alternative to traditional training methods. Its integration into medical education could enhance the development of surgical skills and improve clinical practice outcomes.

Indexed as

Endoscopic Mucosal ResectionHydrogelsModels, AnatomicSimulation TrainingClinical CompetenceGastric MucosaHumansHydrogelsDual-network composite hydrogelsEndoscopic submucosal dissectionGastric tissue simulationMedical training modelsTechnical precision and efficiency

Identifiers

PMID41184750
PMCPMC12581254

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.