ArticleScientific reports2025
Deep‑learning based osteoporosis classification in knee X‑rays using transfer‑learning approach.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Opportunistic Osteoporosis Screening from Routine Knee Radiographs Using a Deep Learning-Based Texture-Branch Cross-Attention Network.Journal of imaging informatics in medicine · 2026Article
- MultiScaleKANNet: a hybrid CNN-KAN-transformer architecture for radiographic bone-loss risk stratification from knee X-rays.Scientific reports · 2026Article
- Deep capsule neural network for identifying anticancer peptides using sequence to image transformation-based local embedded features.BMC biology · 2026Article
- Artificial Intelligence for Osteoporosis Diagnosis, Risk Prediction and Therapy: Current Advances, Clinical Challenges, and Future Perspectives.Clinical interventions in aging · 2026Review
- Enhancing feature selection for ordinal outcomes using resampling-based sparse linear discriminant analysis.Bioinformatics advances · 2026Article
- Identifying protein succinylation sites using generative transformer and a two-dimensional representation with a deep capsule network.iScience · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Bone deterioration from osteoporosis creates fractures that primarily affect females who have reached menopause and older adults. Early detection of osteoporosis requires affordable methods because current diagnostic systems are both expensive and challenging to use. The current application of deep learning models for bone radiography analysis faces three major limitations: shallow architecture, insufficient dataset adaptation, and inadequate feature extraction methods. Talk-based machine learning techniques rely heavily on human-generated feature construction; however, they fail to recognize the delicate image patterns that are present in medical contexts. VGG-16 provides strong power, but businesses must invest in advanced and expensive hardware platforms while maintaining challenges with data quantity. The detection of osteoporosis in knee X-rays through deep learning and the ResNet-50 model using transfer learning remains our primary proposal for solving existing issues. An overview of 372 X-ray images with verified medical information was constructed for T-score ratings determined using a quantitative ultrasound system. Following fine-tuning of our model based on ResNet-50, we achieved 90% accuracy, which exceeded all alternative models tested, including VGG-16 with 88% accuracy using fine-tuning, 80% without fine-tuning, a 3-layer CNN at 66%, ResNet-18 at 79%, and non-fine-tuned ResNet-50 at 83%. The clinical value of the ResNet-50 model stems from its high accuracy, strong sensitivity, and specificity rates. The detection reliability of osteoporosis by the deep transfer learning CNN ResNet-50 has been proven through these findings, which provide healthcare practitioners with an effective diagnostic tool for early detection and prevention of fractures. Our research indicates that deep learning using transfer learning strategies produces a crucial enhancement in medical imaging systems, leading to better patient results.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.