Evidence map›Paper›PMID 41184477›Full record

Observational studyScientific reports2025

Association between smoking status and complete blood cell parameters in baseline data from the Fasa adults cohort study.

Mehdi Sharafi, Elham Haghjoo, Pezhman Bagheri, Mahsa Rostami Chijan, Najibullah Baeradeh, Sima Afrashteh, Ali Mouseli

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mehdi SharafiCellular and Molecular Research Center, Gerash University of Medical Sciences, Gerash, Iran.
Elham HaghjooNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Pezhman BagheriNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Mahsa Rostami ChijanNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
Najibullah BaeradehDepartment of Public Health, Ferdows Faculty of Medical Sciences, Birjand University of Medical Sciences, Birjand, Iran.
Sima AfrashtehDepartment of Biostatistics and Epidemiology, Faculty of Health and Nutrition, Bushehr University of Medical Sciences, Bushehr, Iran. sima.afrashte3@gmail.com.
Ali MouseliSocial Determinants in Health Promotion Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Smoking is one of the most important preventable causes of chronic disease and premature death in adults worldwide. The effect of smoking on blood parameters is not well known, and the results are contradictory. The present study aimed to investigate the association between smoking status and blood parameters of adults in southwestern Iran. This cross-sectional study was conducted using data from the recruitment phase of the Fasa Adults Cohort Study (FACS). A total of 6988 adults participated. The study variables included demographic characteristics, chronic diseases, smoking status, physical activity, and blood cell parameters. Linear regression analyses were performed to examine associations between smoking status and blood parameters. Based on the multivariate linear regression results, current smokers showed higher levels of white blood cells (β = 0.89), hemoglobin (β = 0.14), mean corpuscular volume (β = 1.05), lymphocyte/monocyte ratio (β = 0.75), mean corpuscular hemoglobin concentration (β = 0.18), and mean corpuscular hemoglobin (β = 0.50) compared to non-smokers. Additionally, mean platelet volume was significantly lower in ex-smokers (β = - 0.05) and passive smokers (β = - 0.05) compared to never-smokers. Our results indicate that cigarette smoking is linked to increased levels of specific blood cell parameters. Although smoking clearly affects various hematological measures, inconsistencies in the literature-particularly concerning indices like MPV-highlight the need for more detailed research.

Indexed as

SmokingAdultBlood Cell CountCohort StudiesCross-Sectional StudiesErythrocyte IndicesFemaleHemoglobinsHumansIranMaleMiddle AgedHemoglobinsBlood cell parametersCigarette smokingLymphocyte/Monocyte ratioWhite blood cell

Identifiers

PMID41184477
PMCPMC12583599

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.