Evidence map›Paper›PMID 41184355›Full record

ArticleScientific reports2025

Health risk assessment of potentially toxic elements in bread from Iranian markets using Monte Carlo simulation.

Fateme Asadi Touranlou, Seyedeh Belin Tavakoly Sany, Majid Ghayour Mobarhan, Saeid Khanzadi, Asma Afshari, Mohammad Hashemi

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fateme Asadi Touranlou *Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyedeh Belin Tavakoly Sany *Department of Health, Safety and Environmental Management, Faculty of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
Majid Ghayour MobarhanDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Saeid KhanzadiDepartment of Food Hygiene and Aquaculture, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
Asma AfshariDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad HashemiMedical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Hashemimd@mums.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the nutritional importance of bread in the Iranian diet, ensuring its safety regarding chemical contaminants is crucial. This study assesses the potential health risks posed by heavy metals in bread available in Iran. A total of 248 bread samples were collected from 11 provinces during winter 2020. After sample preparation, the concentration of heavy metals was measured using inductively coupled plasma optical emission spectroscopy. A health risk assessment model was employed to evaluate health effects and carcinogenic potential. The average concentrations of Copper (Cu), Zinc (Zn), Iron (Fe), Cadmium (Cd), Aluminum (Al), Cobalt (Co), Lead (Pb), Chromium (Cr), Nickel (Ni), and Mercury (Hg) were 3.08 ± 1.24, 13.6 ± 44.94, 59.24 ± 30.62, 0.004 ± 0.02, 4.98 ± 2.85, 0.01 ± 0.03, 0.65 ± 1.71, 1 ± 1.42, 0.05 ± 0.23, and 0.03 ± 0.12 mg/kg dry weight, respectively. Notably, the levels of Pb (0.65 ± 1.71 mg/kg) and Cr (1 ± 1.42 mg/kg) exceeded the WHO/FAO and Iranian National Standards threshold levels for both children and adults, indicating potential health risks. Overall, these findings suggest potential health and carcinogenic risks associated with heavy metals contamination in bread. Continuous monitoring of wheat and derived products is recommended to safeguard public health.

Indexed as

BreadFood ContaminationMetals, HeavyHumansIranMonte Carlo MethodRisk AssessmentMetals, HeavyBreadChemical pollutantsFood safetyHealth riskHeavy metalsMonte Carlo simulation

Identifiers

PMID41184355
PMCPMC12583719

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.