ArticleNature communications2025
Powerful one-dimensional scan to detect heterotic quantitative trait loci.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Genetic Dissection of Wheat Heterosis Identifies Candidate Genes in Biparental and Diverse Hybrid Populations.Plant biotechnology journal · 2026Article
- From QTL to candidate genes: a data-driven approach to unravel the genetic architecture of yellow rust resistance in central European wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Association mapping of hybrid seed set and heterosis in a central European multi-parental wheat population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Powerful one-dimensional scan to detect heterotic quantitative trait loci.Nature communications · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
To meet the growing global demand for food, increasing yields through heterosis in agriculture is crucial. A deep understanding of the genetic basis of heterosis has led to the development of a quantitative genetic framework that incorporates both dominance and epistatic effects. However, incorporating all pairwise epistatic interactions is computationally challenging due to the large sequencing depth and population sizes needed to uncover the genes behind complex traits. In this study, we develop hQTL-ODS, a one-dimensional scanning method that directly assesses the net contribution of each quantitative trait locus to heterosis. Simulations show that hQTL-ODS reduces computational time while offering higher power and lower false-positive rate. We apply this method to a population of 5243 wheat hybrids with whole-genome sequenced profile, revealing key epistatic hubs that play a critical role in determining heterosis.
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Registered trials
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