Evidence map›Paper›PMID 41184130›Full record

ReviewCold Spring Harbor perspectives in biology2026

Developing Optogenetic Approaches to Study Ca

Tatsuki Nonomura, Xiaoxuan Liu, Megan Chiu, Zhi Tan, Tien-Hung Lan, Yubin Zhou

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tatsuki Nonomura *Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M University, Houston, Texas 77030, USA.
Xiaoxuan Liu *Center for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M University, Houston, Texas 77030, USA.
Megan ChiuCenter for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M University, Houston, Texas 77030, USA.
Zhi TanCenter for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.
Tien-Hung LanCenter for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M University, Houston, Texas 77030, USA yubinzhou@tamu.edu tienlan08@tamu.edu.
Yubin ZhouCenter for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M University, Houston, Texas 77030, USA yubinzhou@tamu.edu tienlan08@tamu.edu.

Funding

NanoOptogenetic immunotherapy for B cell lymphomaR01CA232017 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HAN, GANG, ZHOU, YUBIN · 2019 to 2023
$2.2M
Engineering Smart Antibody-like Protein Scaffolds with precision switchesR01GM144986 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ZHOU, YUBIN · 2022 to 2025
$1.3M
Synthetic biology toolkit for precise tuning of T cell activityR21AI174606 · NIAID · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ZHOU, YUBIN · 2023 to 2024
$417k
Optogenetic toolkit for precise control of organellar calcium signalingR21GM145063 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ZHOU, YUBIN · 2022 to 2023
$413k
Selective targeting of a Rho GTPase mutant for peripheral T cell lymphoma treatmentR21CA277257 · NCI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ZHOU, YUBIN · 2023 to 2024
$392k
NCI NIH HHS R01 CA232017NCI NIH HHS R21 CA277257NIAID NIH HHS R21 AI174606NIGMS NIH HHS R01 GM144986NIGMS NIH HHS R21 GM145063
6 · The paper itself

Abstract

Calcium ions (Ca

Indexed as

CalciumCalcium SignalingOptogeneticsAnimalsCalcium Release Activated Calcium ChannelsHumansCalciumCalcium Release Activated Calcium Channels

Identifiers

PMID41184130
PMCPMC13102357

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.