Evidence map›Paper›PMID 41183895›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Importance of Vaccine Adjuvants: A Comparative Study of Antibody Acquisition Rates and Levels Before and After Adjuvant Change in the Hepatitis B Vaccine.

Keiichiro Yoneyama, Tatsuya Kurihara, Ayako Tsuboya, Fuyuhiko Yamamura, Yuka Okajima, Daisuke Tanaka

Abstract readComparative Study
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Keiichiro YoneyamaHealth Service Center, Showa University, Japan.
Tatsuya KuriharaDepartment of Hospital Pharmaceutics, Showa University School of Pharmacy, Japan.
Ayako TsuboyaDepartment of Hospital Pharmaceutics, Showa University School of Pharmacy, Japan.
Fuyuhiko YamamuraDepartment of Medicine, Division of Gastroenterology, Showa University School of Medicine, Japan.
Yuka OkajimaHealth Service Center, Showa University, Japan.
Daisuke TanakaHealth Service Center, Showa University, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Hepatitis B (HB) is a significant global public health concern, and the World Health Organization has emphasized the importance of HB vaccination programs. Currently, there are only two commercially available HB vaccines in Japan: HEPTAVAX

Indexed as

Adjuvants, VaccineHepatitis BHepatitis B AntibodiesHepatitis B VaccinesFemaleHepatitis B virusHumansMaleVaccinationYoung AdultAdjuvants, VaccineHepatitis B AntibodiesHepatitis B Vaccinesadjuvanthepatitis B vaccinevaccine antibody acquisition ratesvaccine geometric mean antibody titer

Identifiers

PMID41183895
PMCPMC12659953

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.