Evidence map›Paper›PMID 41183611›Full record

SynthesisIndian heart journal

Cerebral embolic protection devices in transcatheter aortic valve implantation: An updated meta-analysis of randomized controlled trials.

Ensieh Sadat Mansouri, Flavia Queiroga, Mohammadhasan Ghasemi, Lucas Mendes Barbosa, Juan Pinilla, Muhammad Aqib Faizan, Saman Faizollah Zadeh Ardebili, Nihar Jena, Wilton Gomes

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ensieh Sadat MansouriDepartment of Internal Medicine, Ziaeian Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: encyesaadaat@yahoo.com.
Flavia QueirogaDepartment of Medicine, Emory University, Atlanta, USA.
Mohammadhasan GhasemiCardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Lucas Mendes BarbosaDepartment of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Juan PinillaCES University, School of Medicine, Medellin, Colombia.
Muhammad Aqib FaizanGomal Medical College, Khyber Medical University, Peshawar, Pakistan.
Saman Faizollah Zadeh ArdebiliCharles University, Faculty of Medicine in Hradec Králové, Czech Republic.
Nihar JenaDepartment of Interventional Cardiology, Marshall University, Huntington, WV, USA. Electronic address: niharjmd@gmail.com.
Wilton GomesINC Hospital, Department of Interventional Cardiology, Curitiba, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCerebral embolic protection devices (CEPD) have been designed to prevent embolization to the cerebral circulation during transcatheter aortic valve replacement (TAVR). However, the efficacy and safety of CEPD in stroke prevention in TAVR remains uncertain.

methodsPubMed, Embase, and Cochrane Library were searched for randomized controlled trials (RCTs) comparing CEPD vs. control for patients undergoing TAVR. Risk ratios (RR) with 95 % confidence intervals (CI) were pooled with a random-effects model.

resultsOur meta-analysis included eight RCTs with 11,596 patients, of whom 5946 (51 %) were randomized to the CEPD group. There was no significant difference in the incidence of any stroke (3.51 % vs. 3.64 %; RR 0.91; 95 % CI 0.75-1.1; p = 0.33; I

Indexed as

Aortic Valve StenosisEmbolic Protection DevicesIntracranial EmbolismRandomized Controlled Trials as TopicTranscatheter Aortic Valve ReplacementGlobal HealthHumansIncidenceAortic stenosisCEPDSentinelTAVRTriGaurd

Identifiers

PMID41183611
PMCPMC13133527

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.