Evidence map›Paper›PMID 41183509›Full record

ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2026

Kidney replacement therapy trajectories of patients with kidney failure: an ERA Registry study.

Brittany A Boerstra, Anneke Kramer, Kitty J Jager, Miha Arnol, Anders Åsberg, Sevcan A Bakkaloglu, Lukas Buchwinkler, Marta Crespo, Marc A G J Ten Dam, Patrik Finne and 14 more

Abstract read
In one paragraph

Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Brittany A BoerstraERA Registry, Amsterdam UMC location University of Amsterdam, Department of Medical Informatics, Amsterdam, The Netherlands.ORCID 0000-0001-7820-0721
Anneke KramerERA Registry, Amsterdam UMC location University of Amsterdam, Department of Medical Informatics, Amsterdam, The Netherlands.ORCID 0000-0002-7560-2669
Kitty J JagerERA Registry, Amsterdam UMC location University of Amsterdam, Department of Medical Informatics, Amsterdam, The Netherlands.ORCID 0000-0003-0444-8569
Miha ArnolDepartment of Nephrology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Anders ÅsbergDepartment of Transplantation Medicine, Oslo University Hospital and Department of Pharmacy, University of Oslo, Oslo, Norway.
Sevcan A BakkalogluGazi University, Faculty of Medicine, Department of Pediatric Nephrology, Ankara, Türkiye.
Lukas BuchwinklerAustrian Dialysis and Transplantation Registry, Department of Nephrology, University Hospital Innsbruck, Innsbruck, Austria.ORCID 0009-0009-3057-7306
Marta CrespoNephrology Department and Renal Transplant Unit, Hospital del Mar, Barcelona, Spain.
Marc A G J Ten DamDutch Renal Registry, Utrecht, The Netherlands.
Patrik FinneHelsinki University Hospital and University of Helsinki, Department of Nephrology, Helsinki, Finland.
Sergio A García-MarcosNephrology Department and Advanced Chronic Kidney Disease Unit, Hospital Universitario Poniente, Almería, Spain.
Line HeylenNederlandstalige Belgische Vereniging voor Nefrologie, Antwerp, Belgium.ORCID 0000-0002-4595-0195
Kristine HommelDepartment of Nephrology, Holbaek Hospital, Holbaek, Denmark.
Olafur S IndridasonSection of Nephrology, Landspitali University Hospital, Reykjavik, Iceland.
Viktorija KuzemaDepartment of Nephrology, Pauls Stradins Clinical University Hospital, Riga, Latvia.
Antoine LanotNormandie Université, UNICAEN, CHU de Caen Normandie, Néphrologie, Caen, France.
Shona MethvenRenal Unit, Aberdeen Royal Infirmary, Aberdeen, UK.
Alma Mutevelić-TurkovićClinic for Nephrology and Renal Replacement Therapy, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Belén PonteNephrology and Hypertension Division, Department of Medicine, University Hospital of Geneva, Geneva, Switzerland.ORCID 0000-0003-4730-6050
Olga Lucia Rodriguez ArévaloRegistry of Renal Patients of the Valencian Community, General Directorate of Public Health, Ministry of Health, Valencia, Spain.
María O ValentínNephrology Department, Hospital Universitario Marqués de Valdecilla, University of Cantabria, IDIVAL, Santander, Spain.
Alberto OrtizRICORS 2040, Madrid, Spain.ORCID 0000-0002-9805-9523
Vianda S StelERA Registry, Amsterdam UMC location University of Amsterdam, Department of Medical Informatics, Amsterdam, The Netherlands.ORCID 0000-0002-0007-1947
Pietro Manuel FerraroSection of Nephrology, Department of Medicine, Università degli Studi di Verona, Verona, Italy.ORCID 0000-0002-1379-022X

Funding

ERA
6 · The paper itself

Abstract

backgroundTrajectories of patients receiving kidney replacement therapy (KRT), including transitions between hemodialysis (HD), peritoneal dialysis (PD) and kidney transplantation (KTx), may vary across patient subgroups and have not yet been investigated in Europe. This study aimed to: (i) describe the number of shifts across KRT modalities; and (ii) characterize the most frequent patient trajectories, including the direction of shifts across KRT modalities, the duration spent on each modality, and patient events, including death.

methodsData of adult patients (≥20 years) who initiated KRT between 2004 and 2013 were extracted from the European Renal Association (ERA) Registry database and patients were followed for 10 years from the moment of KRT initiation. Results were stratified by age, sex, primary renal disease (PRD), country and initial KRT modality.

resultsAmong 289 323 patients, more than two-thirds (69.6%) remained on their initial KRT modality until death or the end of 10 years follow-up, but younger patients and patients who initiated with PD had more shifts across KRT modalities than others. Overall, the most frequent patient trajectories were HD followed by death (53.4%), HD to KTx (10.2%), remaining on HD for 10 years (5.6%), PD followed by death (4.4%) and PD to KTx (2.9%). The most frequent patient trajectories differed between age and PRD groups, and across European countries, but not between women and men.

conclusionThe number and direction of shifts across KRT modalities varied by age, PRD, country and initial KRT modality, but not by sex. Future research should further investigate trajectories of patient subgroups that stood out, including young HD patients who died on their initial KRT modality and those who remained on HD for 10 years without undergoing KTx.

Indexed as

Kidney Failure, ChronicKidney TransplantationPeritoneal DialysisRegistriesRenal DialysisRenal Replacement TherapyAdultAgedEuropeFemaleFollow-Up StudiesGlomerular Filtration RateHumansKidney Function TestsMaleMiddle Agedhemodialysiskidney transplantationperitoneal dialysispre-emptivetransitions

Identifiers

PMID41183509
PMCPMC13270304

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.