Evidence map›Paper›PMID 41183497›Full record

Observational studyEuropean heart journal. Cardiovascular Imaging2026

Prescriptive appropriateness of echocardiography for the diagnosis of infective endocarditis: an 11-year observational study.

Antonella Cecchetto, Giulia Baroni, Angela Stievano, Stefano Nistri, Giovanni Borile, Donato Mele

Abstract readObservational Study
In one paragraph

Observational study in European heart journal. Cardiovascular Imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antonella CecchettoCardiology Unit, University of Padua-Azienda Ospedaliera, Via Giustiniani 2, 35128 Padua, Italy.ORCID 0000-0003-4069-4177
Giulia BaroniDepartment of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, Via Giustiniani 2, 35128 Padua, Italy.
Angela StievanoDepartment of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, Via Giustiniani 2, 35128 Padua, Italy.
Stefano NistriDepartment of Cardio-Thoraco-Vascular Sciences and Public Health, University of Padua, Via Giustiniani 2, 35128 Padua, Italy.ORCID 0000-0003-4723-6646
Giovanni BorileUOC Sistemi Informativi, University of Padua-Azienda Ospedaliera, Via Giustiniani 2, 35128 Padua, Italy.
Donato MeleCardiology Unit, University of Padua-Azienda Ospedaliera, Via Giustiniani 2, 35128 Padua, Italy.ORCID 0000-0002-2823-4090

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTransthoracic (TTE) and transoesophageal echocardiography (TEE) are fundamental tools in diagnosing infective endocarditis (IE). Although IE remains rare, ultrasound (US) requests are increasing. No long-term data exist regarding the appropriateness of US prescriptions for IE following the 2017 Appropriate Use Criteria (AUC) for Multimodality Imaging in Valvular Heart Disease. METHODS AND

resultsUS requests for suspected IE from September 2013 to June 2024 were reviewed. Patient records were retrieved electronically. Appropriateness was assessed using the 2017 AUC, the 2015 ESC Guidelines for IE management, and the 2013 Guidelines for TEE performance. Over 11 years, 2461 US requests, each referring to a unique hospitalized patient, were analysed. Most patients were males (60.5%), mean age 64 ± 17 years. Positive blood cultures were found in 41.8%, and IE was diagnosed in 10.6%, with a mortality rate of 7.6%. Overall, 1559 (63.4%) US requests were deemed inappropriate, with no significant change after guideline publication (P = 0.078). Specifically, 1402 (64.8%) TTE and 157 (52.7%) initial TEE requests were inappropriate. When TEE was used as a supplemental test, 138 (61.9%) were technically appropriate and 122 (54.7%) clinically appropriate. Cardiologists submitted more appropriate requests (65.8%) than non-cardiologists. Among appropriate requests, IE was confirmed in 15.3% of cases.

conclusionMost US requests for suspected IE were inappropriate, particularly those made by non-cardiologists, highlighting the need for improved adherence to imaging guidelines, with potential benefits for patient care and resource management.

Indexed as

EchocardiographyEchocardiography, TransesophagealEndocarditisAgedFemaleGuideline AdherenceHumansMaleMiddle AgedPractice Guidelines as TopicRetrospective Studiesappropriatenessdiagnosisechocardiographyendocarditis

Identifiers

PMID41183497
PMCPMC12857219

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.