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ArticleBiological trace element research2026

Environmental Arsenic Contamination and Human Health Risk Assessment in the Kosi Plain Region of Bihar, India.

Radhika Agarwal, Arun Kumar, Tejasvi Pandey, Deeksha Verma, Kanhaiya Kumar, Nirmal Kumar Chayal, Pushkar Kumar, Nikhil Kumar, Mohammad Ali, Abhinav Srivastava and 4 more

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Article in Biological trace element research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Cadmium Toxicity toMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Radhika AgarwalMahavir Cancer Sansthan & Research Centre, Patna, Bihar, India.
Arun KumarMahavir Cancer Sansthan & Research Centre, Patna, Bihar, India. drarunk31@gmail.com.ORCID http://orcid.org/0000-0002-8946-5909
Tejasvi PandeyLovely Professional University, Phagwara, Punjab, India. tejasvi1313@gmail.com.
Deeksha VermaLovely Professional University, Phagwara, Punjab, India.
Kanhaiya KumarMahavir Cancer Sansthan & Research Centre, Patna, Bihar, India.
Nirmal Kumar ChayalAmity University Rajasthan, Jaipur, Rajasthan, India.
Pushkar KumarMahavir Cancer Sansthan & Research Centre, Patna, Bihar, India.
Nikhil KumarMahavir Cancer Sansthan & Research Centre, Patna, Bihar, India.
Mohammad AliMahavir Cancer Sansthan & Research Centre, Patna, Bihar, India.
Abhinav SrivastavaMahavir Cancer Sansthan & Research Centre, Patna, Bihar, India.
Kumar Sambhav VermaAmity University Rajasthan, Jaipur, Rajasthan, India.
Dhruv KumarUniversity of Petroleum and Energy Studies, Dehradun, Uttarakhand, India.
Ashok SharmaAll India Institute of Medical Sciences, New Delhi, India.
Ashok Kumar GhoshMahavir Cancer Sansthan & Research Centre, Patna, Bihar, India.

Funding

Indian Council of Medical Research ICMR F.No. 5/10/FR/79/2020-RBMCH, Dated 09/08/2021
6 · The paper itself

Abstract

Groundwater arsenic poisoning in the recent times has caused serious health hazards to the exposed population of Bihar. The arsenic causing disease burden in the Gangetic plains of Bihar has been well documented. But the present study aims to find out the arsenic exposure in the Kosi River plain region of Bihar for the first time. This study investigates arsenic exposure through breastfeeding among children in Bihar’s Kosi region -Madhepura, Saharsa, Supaul, Katihar districts while Bhagalpur and Nalanda in the Gangetic plain region where groundwater arsenic poisoning poses severe health risks. From a cohort of n = 312 lactating women, breast milk, blood, and urine samples, along with urine samples from n = 101 breastfed infants, were analyzed. Results show 25.3% of breast milk samples exceeded the WHO limit of 0.64 µg/L, with elevated levels also in maternal blood and urine samples. Infant’s urine indicated 2% above the permissible limit (< 50 µg/L). The multivariate study reveals a moderate to strong correlation between water arsenic levels and arsenic accumulation in rice. As water arsenic contamination increases, rice arsenic content also increases, indicating a significant uptake from irrigation. This underscores the role of rice as a major dietary source of arsenic in the studied area. The Monte Carlo simulation study shows the exceeding carcinogenic risk assessment in the rice samples as 79.94% in comparison to the breastmilk samples 1.73%. In conclusion, additional research in the Kosi region is imperative to thoroughly tackle this health challenge, with far-reaching implications for the well-being of future generations.

Indexed as

ArsenicEnvironmental ExposureWater Pollutants, ChemicalAdultArsenic PoisoningEnvironmental MonitoringFemaleFood ContaminationGroundwaterHumansIndiaInfantMilk, HumanOryzaRisk AssessmentArsenicWater Pollutants, ChemicalArsenic exposureBreastmilkChild exposureHealth risk

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.