Evidence map›Paper›PMID 41182599›Full record

Observational studyJournal of clinical monitoring and computing2025

Nociception level index response to pacemaker stimulation.

Cosmin Balan, Robert-Thomas Barbulescu, Andrei Dumitrache, Antonia Fodoroiu, Bianca Morosanu, Alexandru Nica, Iulia Stanculea, Irina Stoian, Liana Valeanu, Adrian Wong and 1 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of clinical monitoring and computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cosmin Balan1 st Department of Cardiovascular Anesthesia and Intensive Care Medicine, Prof. Dr. C.C. Iliescu Institute for Emergency Cardiovascular Diseases, Bucharest, Romania. cosmin13mara@yahoo.com.ORCID 0000-0002-1477-6390
Robert-Thomas Barbulescu1 st Department of Cardiovascular Anesthesia and Intensive Care Medicine, Prof. Dr. C.C. Iliescu Institute for Emergency Cardiovascular Diseases, Bucharest, Romania.
Andrei Dumitrache1 st Department of Cardiovascular Anesthesia and Intensive Care Medicine, Prof. Dr. C.C. Iliescu Institute for Emergency Cardiovascular Diseases, Bucharest, Romania.
Antonia Fodoroiu1 st Department of Cardiovascular Anesthesia and Intensive Care Medicine, Prof. Dr. C.C. Iliescu Institute for Emergency Cardiovascular Diseases, Bucharest, Romania.
Bianca Morosanu1 st Department of Cardiovascular Anesthesia and Intensive Care Medicine, Prof. Dr. C.C. Iliescu Institute for Emergency Cardiovascular Diseases, Bucharest, Romania.
Alexandru NicaCentre Hospitalier de Compiègne-Noyon, Noyon, France.
Iulia Stanculea1 st Department of Cardiovascular Anesthesia and Intensive Care Medicine, Prof. Dr. C.C. Iliescu Institute for Emergency Cardiovascular Diseases, Bucharest, Romania.
Irina Stoian1 st Department of Cardiovascular Anesthesia and Intensive Care Medicine, Prof. Dr. C.C. Iliescu Institute for Emergency Cardiovascular Diseases, Bucharest, Romania.
Liana Valeanu1 st Department of Cardiovascular Anesthesia and Intensive Care Medicine, Prof. Dr. C.C. Iliescu Institute for Emergency Cardiovascular Diseases, Bucharest, Romania.
Adrian WongDepartment of Critical Care, Kings College Hospital, London, UK.
Serban-Ion Bubenek-Turconi1 st Department of Cardiovascular Anesthesia and Intensive Care Medicine, Prof. Dr. C.C. Iliescu Institute for Emergency Cardiovascular Diseases, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Nociception Level (NOL) index of the PMD-200™ monitor measures intraoperative nociception-antinociception balance. Because it relies on photoplethysmography, it may be affected by pacemaker interference. We evaluated its response to pacemaker stimulation in the absence of nociceptive input. Mechanically ventilated adults after elective cardiac surgery were studied. NOL index, bispectral index, mean arterial pressure, and heart rate were recorded every minute for 35 min across seven five-minute periods: baseline (pacemaker off), pacing at 90 beats.min

Indexed as

Monitoring, IntraoperativeNociceptionPacemaker, ArtificialAdultAgedAged, 80 and overCardiac Surgical ProceduresConsciousness MonitorsElectroencephalographyFemaleHeart RateHumansMaleMiddle AgedPhotoplethysmographyRespiration, ArtificialCardiac surgeryNociception-antinociception balanceNociception level indexPacemaker

Identifiers

PMID41182599

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.