ReviewApplied biochemistry and biotechnology2026
Diatom-Derived Biochemicals: An In-Depth Analysis of Polysaccharides, Extraction Methodologies, and Diverse Applications.
Review in Applied biochemistry and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A framework for microalgal biosorption of heavy metals: mechanisms, modeling, and critical insights.RSC advances · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Diatoms are unicellular eukaryotic algae, renowned for their intricately patterned silica cell walls, which exhibit remarkable morphological precision and nanostructural complexity. They possess a unique and rich biochemical profile and are prolific producers of biologically active polysaccharides, broadly categorized as intracellular, extracellular (primarily sulfated), and cell wall-associated types. These polysaccharides play vital roles in biofilm formation, carbon cycling, nutrient storage, and ecosystem dynamics, while also holding substantial promises in commercial and biotechnological fields. This review provides an integrated overview of diatom polysaccharide chemotypes-storage β-glucans, cell-wall uronic- and sulfate-rich scaffolds, and extracellular exopolymers-and evaluates the conventional versus emerging extraction and purification techniques, discussing trade-offs in yield, selectivity, and polymer integrity. The diverse structural characterization methods for elucidating monosaccharide linkages and functional modifications have been reviewed. The genomic and metabolic insights into polysaccharide biosynthesis have been elaborated along with elucidation of the relationship between extracellular polymeric substances and bacterial community assembly. The multifaceted applications of diatom-derived polysaccharides in carbon sequestration, biomedicine (e.g., anticoagulant, antioxidant, antiviral, anticancer, immunomodulatory agents), materials science, and environmental remediation has been discussed along with the current challenges-species variability, efficient frustule disruption, and scalable processing. The-genomics-guided strain optimization and sustainable bioprocess design holds immense future potential for diatom derive polysaccharides.
Indexed as
Identifiers
41182542What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.