Evidence map›Paper›PMID 41182538›Full record

Trial reportEuropean journal of drug metabolism and pharmacokinetics2026

Bioavailability and Cellular Compatibility of a Novel Coenzyme Q

Ailin C Avila, Ezequiel Bernabeu, Diego Chiappetta, Ana M Rojas, Valeria P Tripodi

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of drug metabolism and pharmacokinetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ailin C AvilaDepartamento de Industrias, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Int. Güiraldes 2620, Ciudad Universitaria, C1428BGA, Buenos Aires, Argentina.
Ezequiel BernabeuDepartamento de Tecnología Farmacéutica, Universidad de Buenos Aires, Junín 954, C1113AAD, Buenos Aires, Argentina.
Diego ChiappettaDepartamento de Tecnología Farmacéutica, Universidad de Buenos Aires, Junín 954, C1113AAD, Buenos Aires, Argentina.
Ana M RojasDepartamento de Industrias, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Int. Güiraldes 2620, Ciudad Universitaria, C1428BGA, Buenos Aires, Argentina.
Valeria P TripodiDepartamento de Química Analítica y Fisicoquímica, Universidad de Buenos Aires, Junín 954, C1113AAD, Buenos Aires, Argentina. vtripodi@ffyb.uba.ar.ORCID http://orcid.org/0000-0003-2106-7127

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas PIP 11220170100632COConsejo Nacional de Investigaciones Científicas y Técnicas PIP 11220210100622COSecretaria de Ciencia y Tecnica, Universidad de Buenos Aires 20020190100034BASecretaria de Ciencia y Tecnica, Universidad de Buenos Aires 20020220300091BA
6 · The paper itself

Abstract

backgroundCoenzyme Q

objectiveTo evaluate the bioavailability and cellular compatibility of this novel CoQ

methodsTwo exploratory studies were conducted in healthy adults: a randomized cross-over single-dose trial (n = 6) and a 14-day repeated-dose trial (n = 12) comparing 1 g of CoQ

resultsThe single-dose study in healthy adults demonstrated equivalent bioavailability of 1 g CoQ

conclusionsThese findings indicate that the emulgel matrix does not compromise the bioavailability of oil-dissolved CoQ

Indexed as

Deglutition DisordersUbiquinoneAdministration, OralAdultAnimalsBiological AvailabilityChlorocebus aethiopsCross-Over StudiesDrug Delivery SystemsFemaleGelsHumansMaleMiddle AgedVero CellsYoung Adultcoenzyme Q10GelsUbiquinone

Identifiers

PMID41182538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.