Evidence map›Paper›PMID 41182522›Full record

ArticleInternational ophthalmology2025

Application of ultra-wide-field optical coherence tomography angiography in detecting peripheral lattice degeneration.

Chunyang Cai, Peiyu Liu, Qingquan Wei, Jiawei Huang, Lan Yi, Fang Wei, Qinghua Qiu, Chao Song

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In one paragraph

Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chunyang Cai *Department of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xianxia Road, Changning, Shanghai, People's Republic of China.
Peiyu Liu *Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Qingquan Wei *Department of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xianxia Road, Changning, Shanghai, People's Republic of China.
Jiawei HuangDepartment of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xianxia Road, Changning, Shanghai, People's Republic of China.
Lan YiDepartment of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xianxia Road, Changning, Shanghai, People's Republic of China.
Fang WeiDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Qinghua QiuDepartment of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xianxia Road, Changning, Shanghai, People's Republic of China. qinghuaqiu@163.com.
Chao SongDepartment of Ophthalmology, Tong Ren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xianxia Road, Changning, Shanghai, People's Republic of China. aiersc@163.com.

Funding

Fundamental Research Funds for the Central Universities YG2024LC13National Natural Science Foundation of China 82371072Research Fund of Shanghai Tongren Hospital, Shanghai Jiaotong University School of Medicine 2023DHYGJC-YBA06
6 · The paper itself

Abstract

purposeThis study aims to characterize retinal and vitreous morphological changes in peripheral lattice degeneration using ultra-wide-field optical coherence tomography angiography (UWF-OCTA) guided by scanning laser ophthalmoscope (SLO) and to provide illustrative clinical applications.

methodsA total of 15 eyes from 15 patients with peripheral retinal lattice degeneration were enrolled between January 2024 and March 2024. Peripheral lattice lesions were localized by SLO, followed by optical coherence tomography (OCT) and UWF-OCTA to evaluate retinal and vitreous changes.

resultsUWF-OCTA identified diverse retinal and vitreous changes in LD, including vitreous traction, retinal rupture, retinal thinning, vitreous detachment, and subretinal fluid collection. Clinical cases demonstrated that UWF-OCTA may detect lesion details missed by OCT, especially tiny retinal rupture holes.

conclusionUWF-OCTA enables high-resolution imaging of peripheral retina and comprehensive visualization of retinal and vitreous changes across lesion areas. SLO-guided UWF-OCTA shows potential as a supplementary imaging tool for visualizing subtle retinal lesions in peripheral lattice degeneration, laying the groundwork for future studies on its role in guiding clinical decisions.

Indexed as

AngiographyRetinal DiseasesTomography, Optical CoherenceAdultAgedFemaleHumansMaleOphthalmoscopyRetinaVitreous BodyOptical coherence tomography (OCT)Preventive treatmentRetinal lattice degeneration (LD)Scanning laser ophthalmoscope (SLO)Ultra-wide-field optical coherence tomography angiography (UWF-OCTA)

Identifiers

PMID41182522
PMCPMC12583434

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.