Evidence map›Paper›PMID 41182504›Full record

ReviewClinical journal of gastroenterology2026

PEComas of the colon and rectum: a case report of a 15-year-old girl and a review of the pertinent literature.

Yuriko Yamada, Ai Sadatomo, Homare Ito, Koji Koinuma, Hisanaga Horie, Toshiki Mimura, Seiichi Hirota, Hironori Yamaguchi

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Clinical journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuriko YamadaDivision of Gastroenterological, General and Transplant Surgery, Department of Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.
Ai SadatomoDivision of Gastroenterological, General and Transplant Surgery, Department of Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan. r0626as@gmail.com.ORCID http://orcid.org/0000-0001-5721-2619
Homare ItoDivision of Gastroenterological, General and Transplant Surgery, Department of Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.
Koji KoinumaDivision of Gastroenterological, General and Transplant Surgery, Department of Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.
Hisanaga HorieDepartment of Surgery, Japan Community Health Care Organization Utsunomiya, Utsunomiya, Japan.
Toshiki MimuraDivision of Gastroenterological, General and Transplant Surgery, Department of Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.
Seiichi HirotaDepartment of Pathology, Hyogo Medical University, Nishinomiya, Japan.
Hironori YamaguchiDivision of Gastroenterological, General and Transplant Surgery, Department of Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms characterized by perivascular epithelioid cells. PEComas include angiomyolipoma (AML) of the kidney, clear-cell sugar tumor (CCST), lymphangioleiomyomatosis (LAM) and clear-cell tumors of other anatomical locations. PEComas other than AML, CCST and LAM are very rare tumors that have been referred to as PEComa-not otherwise specified (PEComa-NOS). Especially, colorectal PEComa-NOS remains very rare. A 15-year-old girl underwent a colonoscopy due to hematochezia, thus revealing a 30 mm intramural mass in the upper rectum. The patient was treated by laparoscopic high anterior resection under the diagnosis of Gastrointestinal stromal tumor. Histologically the tumor was positive for HMB45 (human melanoma black 45), TFE3 (transcription factor binding to IGHM enhancer 3), which suggested the diagnosis of PEComa-NOS. The patient remains recurrence-free at five years postoperatively. The treatment strategy, prognosis, and biological behavior of PEComa-NOS is still unclear. We also review the pertinent literature on colorectal PEComa-NOS.

Indexed as

Perivascular Epithelioid Cell NeoplasmsRectal NeoplasmsAdolescentBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsColorectal NeoplasmsFemaleHumansTomography, X-Ray ComputedBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsTFE3 protein, humanPEComaRare tumorRectum

Identifiers

PMID41182504

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.