ArticleInternal and emergency medicine2025
24-Month assessment of respiratory function in patients hospitalized for severe SARS-CoV-2 pneumonia: a follow-up study.
Article in Internal and emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Impact of SARS-CoV-2 Infection on Pulmonary Function in the PURE-Colombia Cohort: A Comparative Analysis with Pre-COVID Values and Non-COVID-19 Controls.Journal of clinical medicine · 2026Article
- Clinical predictors of impaired pulmonary diffusing capacity in patients recovering from COVID-19: A secondary analysis of multicentre datasets.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2026Article
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Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Long COVID affects multiple body systems, with the respiratory system being particularly vulnerable. This study aimed to analyze the lung ventilatory function and diffusion capacity of patients with severe SARS-CoV-2 pneumonia during a 24-month follow-up course. Ventilatory function and lung diffusion capacity were assessed 6, 12, 18, and 24 months after hospital discharge. Ventilatory parameters, Diffusion Lung Carbon Monoxide (DLCO), and KCO (Carbon Monoxide transfer coefficient) normalization were defined as achieving values > 80% predicted. A total of 222 patients admitted to the Intensive Care Unit (ICU) at ASST Spedali Civili di Brescia, Brescia, Italy, were enrolled. Among the 172 patients who completed the study, 140 (63%) achieved normalization of ventilatory parameters, DLCO, and KCO. The median time to recovery was 4.5 months, and the hazard ratio (HR) decreased by 2% for each year of age increase. The median time to normalize ventilatory parameters (VC, FVC, FEV
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