Evidence map›Paper›PMID 41182486›Full record

ArticleAnnals of surgical oncology2026

Risk Factors and Incidence of Reoperation in Direct-to-Implant Breast Reconstruction Surgery Among Patients with Breast Cancer.

Jin Ah Lee, Hye Sun Lee, Soyoung Jeon, Dooreh Kim, Young Joo Lee, Soo Youn Bae, Woo-Chan Park, Chang Ik Yoon, Jangyoun Choi

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Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jin Ah LeeDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Hye Sun LeeBiostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea.
Soyoung JeonBiostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Republic of Korea.
Dooreh KimDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Young Joo LeeDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Soo Youn BaeDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Woo-Chan ParkDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Chang Ik YoonDivision of Breast Surgery, Department of Surgery, College of Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea. fayn03@catholic.ac.kr.
Jangyoun ChoiDepartment of Plastic and Reconstructive Surgery, College of Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea. jycprs@gmail.com.

Funding

National Research Foundation of Korea NRF-2021R1I1A1A01049056
6 · The paper itself

Abstract

backgroundThe increasing incidence of breast cancer leads to the increasing number of mastectomies and frequency of immediate breast reconstruction, particularly using direct-to-implant (DTI) methods. Capsular contracture remains a significant complication in DTI reconstruction, accounting for 10-20% of patients. This study aimed to investigate the incidence and risk factors for capsular contracture in patients with breast cancer undergoing DTI reconstruction using a nationwide cohort in Korea. PATIENTS AND

methodsThis retrospective cohort study used data from the Korean Health Insurance Review and Assessment Service. Patients with ductal carcinoma in situ or invasive breast cancer who underwent mastectomy and immediate DTI reconstruction from January 2015 to December 2018 were included. Risk factors were analyzed using Cox proportional hazard models.

resultsAmong 124,237 patients with breast cancer, 4054 underwent immediate DTI reconstruction, with 552 (13.6%) developing capsular contractures requiring surgery. Among the affected patients, 335, 124, and 93 underwent capsulectomy only, both capsulectomy and implant change, and implant change only, respectively. In multivariable Cox analysis, older age (per 10 years: HR 1.25, 95% CI 1.10-1.41, p < 0.001), radiotherapy (HR 1.44, 95% CI 1.11-1.87, p = 0.006), and lymphedema (HR 2.23, 95% CI 1.60-3.09, p < 0.001) were significantly associated with contracture risk.

conclusionsIn patients with breast cancer undergoing DTI reconstruction, age, radiotherapy, and lymphedema were significant risk factors for capsular contracture. These findings highlight the importance of individualized preoperative planning and counseling to reduce the risk and improve outcomes. Further research should focus on developing strategies to manage these identified risk factors and prevent capsular contracture.

Indexed as

Breast ImplantationBreast ImplantsBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingMammaplastyMastectomyPostoperative ComplicationsReoperationAdultAgedFemaleFollow-Up StudiesHumansIncidenceMiddle Aged

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.