ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026
Accelerometer-measured weekly and diurnal moderate-to-vigorous physical activity patterns and incident osteoporosis.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Physical activity levels and quality of life in osteoporosis patients.Frontiers in sports and active living · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
This study investigated accelerometer-derived MVPA patterns and osteoporosis risk. Weekend warrior pattern demonstrated comparable osteoporosis risk reduction to regular activity. Performing MVPA maximally reduces osteoporosis risk in elderly and high-genetic-risk individuals, and evening/mid-morning timing offers optimal protection. Findings guide personalized exercise timing to mitigate osteoporosis, especially for vulnerable groups. PURPOSE: This study investigated the association between accelerometer-measured "weekend warrior (WW)" pattern and the risk of osteoporosis and also explored the differential impacts of diurnal moderate-to-vigorous physical activity (MVPA) patterns on osteoporosis risk.
methodsWe included 69,310 UK Biobank participants with valid wrist-worn accelerometer data. Based on World Health Organization (WHO) guidelines (≥ 150.0 min/week), we categorized participants as inactive (MVPA < 150.0 min/week), active regular (MVPA ≥ 150.0 min/week and ≥ 50% of total MVPA occurred within > 2 days), and active WW (MVPA ≥ 150.0 min/week and ≥ 50% of total MVPA occurred within 1-2 days). For guideline-adherent individuals, diurnal MVPA patterns were classified via K-means clustering based on hourly activity distribution. The study outcome was incident osteoporosis. Osteoporosis cases were identified using International Classification of Diseases 10th Revision (ICD-10) codes M80, M81, and M82 within the "first occurrence" field.
resultsDuring a median follow-up of 7.7 years, 1544 participants developed osteoporosis (OP). In multivariable-adjusted models, both active WW (HR: 0.78, 95% CI: 0.69-0.89) and active regular (HR: 0.77, 95% CI: 0.67-0.87) participants demonstrated comparable and statistically significant risk reductions compared with inactive individuals. For diurnal MVPA patterns, we used the early-afternoon group as the reference; the evening and mid-morning groups exhibited equivalent risk reductions, and they were (HR: 0.67, 95% CI: 0.52-0.87) and (HR: 0.69, 95% CI: 0.54-0.87), respectively. The early-morning group was associated with modest risk reduction (HR: 0.77, 95% CI: 0.64-0.92).
conclusionsAccumulating MVPA predominantly within 1-2 days confers osteoprotective benefits comparable to evenly distributed weekly activity. Furthermore, the optimal time for osteoporosis risk reduction occurs during evening and mid-morning, followed by early-morning.
Indexed as
Identifiers
41182406What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.