Selective utilization of formic acid and acetic acid in succinic acid fermentation broth to produce single-cell protein using Rhodotorula glutinis.

Fuqiang Liu, Pengfei Wu, Lin Yu, Zitu Lü, Xinying Sun, Jiaxin Li, Lei Liu, Jing Wu, Jianan Zhang

Abstract read

In one paragraph

Article in Bioprocess and biosystems engineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Fuqiang LiuShanxi Key Laboratory of Chemical Product Engineering, College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.

Pengfei WuSchool of Advanced Agriculture and Bioengineering, Yangtze Normal University, Chongqing, 408100, PR China.

Lin YuShanxi Key Laboratory of Chemical Product Engineering, College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.

Zitu LüShanxi Key Laboratory of Chemical Product Engineering, College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.

Xinying SunShanxi Key Laboratory of Chemical Product Engineering, College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.

Jiaxin LiShanxi Key Laboratory of Chemical Product Engineering, College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.

Lei LiuShanxi Key Laboratory of Chemical Product Engineering, College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.

Jing WuShanxi Key Laboratory of Chemical Product Engineering, College of Chemistry and Chemical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China. wujing02@tyut.edu.cn.

Jianan ZhangInstitute of Nuclear and New Energy Technology, Tsinghua University, Beijing, 100084, China. zhangja@tsinghua.edu.cn.

Funding

Jianan Zhang RH2400001651Jing Wu RH2100001380Pengfei Wu CSTB2024NSCQ-MSX0381

6 · The paper itself

Abstract

Microbial fermentation for succinic acid production has the advantages of a short production cycle, renewable raw materials, and mild reaction conditions, and is recognized as a promising green approach. However, the succinic acid fermentation process is often accompanied by by-products such as formic acid and acetic acid, which increase the cost of subsequent separation and waste resources. This study proposed a green integrated process in which Rhodotorula glutinis As2.703 was used to selectively metabolize formic acid and acetic acid in succinic acid fermentation broth to produce high-value-added single-cell protein (SCP), while succinic acid was retained. The results showed that R. glutinis As2.703 achieved a utilization rate of 100% for formic acid and acetic acid in succinic acid fermentation broth, with a biomass of 7.05 g/L and a biomass yield of 0.46 g/g. The protein, lipid, and carotenoid contents in SCP were 53.11%, 16.65%, and 194.15 µg/g, respectively. SuperPro Designer

Indexed as

Acetic AcidFermentationFormatesFungal ProteinsRhodotorulaSuccinic AcidBiomassDietary ProteinsAcetic AcidDietary ProteinsFormatesformic acidFungal Proteinssingle cell proteinsSuccinic AcidBy-productsProcess simulationRhodotorula glutinisSingle-cell proteinSuccinic acid

Identifiers

PMID41182364

DOI10.1111/jpn.13375

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