Evidence map›Paper›PMID 41182031›Full record

ArticleVeterinary medicine and science2025

Central Nervous System Vasculitis Due to Ehrlichia canis in a Dog.

Miguel Benito Benito, Elisabet Dominguez, Nora Romero-Fernández

Abstract readCase Reports
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Miguel Benito BenitoHamilton Specialist Referrals, Part of IVC Evidensia, High Wycombe, Buckinghamshire, UK.
Elisabet DominguezAnicura Ars Veterinaria, Barcelona, Catalunya, Spain.
Nora Romero-FernándezHamilton Specialist Referrals, Part of IVC Evidensia, High Wycombe, Buckinghamshire, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 4-year-old female neutered crossbreed dog was presented for a 2-month history of intermittent vestibulo-cerebellar ataxia and right head tilt. On admission, she presented clinical signs compatible with right paradoxical vestibular syndrome. Haematology showed moderate lymphocytosis, thrombocytopenia and hyperproteinaemia with hyperglobulinemia. Magnetic resonance imaging of the brain showed multiple, bilateral, ill-defined lesions involving the white matter of the brainstem, cerebellum and forebrain with strong diffuse meningeal contrast enhancement. Cerebrospinal fluid cytology showed lymphocytic pleocytosis, and Ehrlichia spp. serology was positive. Treatment with doxycycline showed clinical improvement within 24 h, treatment was continued for 6 weeks. A follow-up magnetic resonance imaging study was performed after treatment and showed complete resolution of the previous lesions. Cerebrospinal fluid analysis showed only albumin-cytological dissociation. Since treatment initiation, the patient remained asymptomatic. Three months after hospital discharge, no further episodes were reported.

Indexed as

Dog DiseasesEhrlichia canisEhrlichiosisAnimalsAnti-Bacterial AgentsDogsDoxycyclineFemaleMagnetic Resonance ImagingAnti-Bacterial AgentsDoxycyclineDogErlichiameningoencephalitisMRIvasculitis

Identifiers

PMID41182031
PMCPMC12581152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.