Evidence map›Paper›PMID 41181933›Full record

ArticleeLife2025

Insight into the bioactivity and action mode of betulin, a candidate aphicide from plant metabolite, against aphids.

Junxiu Wang, Matthana Klakong, Qiuyu Zhu, Jinting Pan, Yudie Duan, Lirong Wang, Yong Li, Jiangbo Dang, Danlong Jing, Hong Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Junxiu Wang *Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), Chongqing Key Laboratory of Forest Ecological Restoration and Utilization in the Three Gorges Reservoir Area, College of Horticulture and Landscape Architecture, Southwest University, Chongqing, China.ORCID https://orcid.org/0000-0002-6453-3477
Matthana Klakong *College of Plant Protection, Southwest University, Chongqing, China.
Qiuyu ZhuCollege of Plant Protection, Southwest University, Chongqing, China.
Jinting PanKey Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), Chongqing Key Laboratory of Forest Ecological Restoration and Utilization in the Three Gorges Reservoir Area, College of Horticulture and Landscape Architecture, Southwest University, Chongqing, China.
Yudie DuanKey Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), Chongqing Key Laboratory of Forest Ecological Restoration and Utilization in the Three Gorges Reservoir Area, College of Horticulture and Landscape Architecture, Southwest University, Chongqing, China.
Lirong WangZhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Zhengzhou, China.
Yong LiZhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Zhengzhou, China.
Jiangbo DangKey Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), Chongqing Key Laboratory of Forest Ecological Restoration and Utilization in the Three Gorges Reservoir Area, College of Horticulture and Landscape Architecture, Southwest University, Chongqing, China.
Danlong JingKey Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River (Ministry of Education), Chongqing Key Laboratory of Forest Ecological Restoration and Utilization in the Three Gorges Reservoir Area, College of Horticulture and Landscape Architecture, Southwest University, Chongqing, China.
Hong ZhouCollege of Plant Protection, Southwest University, Chongqing, China.ORCID https://orcid.org/0000-0003-2438-622X

Funding

Fundamental Research Fund for the Central Universities of China SWU-KR25018National Natural Science Foundation of China 32302394National Natural Science Foundation of China 32402492Sichuan Science and Technology Program 2025ZNSFSC1120Special Funding for Chongqing Postdoctoral Research Project 2312013543265057
6 · The paper itself

Abstract

Pest-resistant plants usually utilize secondary metabolites to cope with insect infestation. Betulin, a key bioactive compound in aphid-resistant wild peach, possesses promising applications in crop protection. Here, betulin, in both greenhouse and field experiments, displayed excellent control efficacy against

Indexed as

AphidsInsecticidesTriterpenesAnimalsBetulinic AcidMolecular Docking SimulationReceptors, GABA-AbetulinBetulinic AcidInsecticidesReceptors, GABA-ATriterpenesaphidbetulinbiochemistrychemical biologyD. melanogasterGABAA receptorinsecticidal mechanisminsecticide

Identifiers

PMID41181933
PMCPMC12582564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.