Evidence map›Paper›PMID 41181847›Full record

ReviewEClinicalMedicine2025

Risk factors for neonatal mortality: an umbrella review of systematic reviews and meta-analyses.

Bereket Kefale, Jonine Jancey, Amanuel T Gebremedhin, Daniel Gashaneh Belay, Sylvester Dodzi Nyadanu, Gavin Pereira, Gizachew A Tessema

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in EClinicalMedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bereket KefaleCurtin School of Population Health, Curtin University, Perth, Western Australia, Australia.
Jonine JanceyCurtin School of Population Health, Curtin University, Perth, Western Australia, Australia.
Amanuel T GebremedhinCurtin School of Population Health, Curtin University, Perth, Western Australia, Australia.
Daniel Gashaneh BelayCurtin School of Population Health, Curtin University, Perth, Western Australia, Australia.
Sylvester Dodzi NyadanuCurtin School of Population Health, Curtin University, Perth, Western Australia, Australia.
Gavin PereiraCurtin School of Population Health, Curtin University, Perth, Western Australia, Australia.
Gizachew A TessemaCurtin School of Population Health, Curtin University, Perth, Western Australia, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Neonatal mortality (NM) remains a persistent global public health challenge, necessitating a comprehensive understanding of its associated risk factors to guide effective interventions. Despite multiple systematic reviews and meta-analyses varying in quality, scope, and conclusions, an umbrella review synthesising this evidence was lacking. Methods: We conducted an umbrella review using six major databases: Embase, Medline, Global Health, CINAHL, Web of Science, and Scopus, along with regional databases, systematic review repositories, and grey literature sources. Eligible studies were systematic reviews and meta-analyses published from 1990 to 22 July 2025 reporting associations between risk factors and all-cause NM based on at least two primary studies. The quality of the reviews was assessed using a measurement tool to assess systematic reviews (AMSTAR-2). Evidence on risk factors was summarised and graded. The review protocol was registered with PROSPERO (CRD42023455542). Findings: Of 10,610 retrieved records, 64 systematic reviews and meta-analyses were included, five of which were systematic reviews without meta-analyses. We identified 54 unique risk factors across 73 outcome-exposure associations. Interpretation: This umbrella review identified Funding: None.

Indexed as

Antenatal careHealth facility deliveryNeonatal mortalityPreterm birthRisk factorsUmbrella review

Identifiers

PMID41181847
PMCPMC12572802

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.