ArticleCureus2025
Hypocalcemia Revisited: Thinking Outside the Box!
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This case report details the presentation of a 62-year-old man with a background of hypothyroidism, hypertension, and chronic kidney disease (CKD) who experienced fatigue with acute-on-chronic hypocalcemia. Despite receiving oral calcium carbonate with vitamin D3 (cholecalciferol) supplementation in primary care, persistent hypocalcemia in the absence of significant renal impairment and a positive response to alfacalcidol (1α-hydroxycholecalciferol) prompted further investigation into genetic causes. A final diagnosis of pseudohypoparathyroidism type 1b (PHP1b) was confirmed through genetic studies. In cases of pseudohypoparathyroidism (PHP), appropriate monitoring and timely management are essential for patient safety and favorable outcomes. This case explores the systematic approach required in the assessment of chronic hypocalcemia to discern aetiology among a wider range of differentials.
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