Evidence map›Paper›PMID 41181743›Full record

ArticleCureus2025

Mediastinal Masses and Sternotomies: A Case Series.

Joshua S Braganza, Michelle Davis, Caroline M Darch, Nadj L Pierre, Annis Ali

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joshua S BraganzaSurgery, Wellspan York Hospital, York, USA.
Michelle DavisSurgery, Drexel University College of Medicine, Philadelphia, USA.
Caroline M DarchSurgery, Wellspan York Hospital, York, USA.
Nadj L PierreSurgery, Wellspan York Hospital, York, USA.
Annis AliThoracic Surgery, Wellspan York Hospital, York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mediastinal masses or cervical masses with mediastinal extension can pose technical challenges when resection is chosen as the intervention of choice. In modern medicine, there are high volumes of minimally invasive approaches, and open surgery is becoming less common. Differentials for mediastinal masses include thymic tumors, thyroid masses, lymphomas, nerve tumors, and bronchogenic lesions, to name a few. The authors describe two open approaches to mediastinal lesions, including a thyroid with mediastinal extension and a paraganglioma, which were both resected via the open approach through sternotomy and hemi-sternotomy. The first case was an 83-year-old female with a large thyroid goiter causing globus sensation and a workup consistent with a large thyroid goiter with mediastinal extension near the tracheo-esophageal groove, requiring sternotomy for resection. The second case was a 50-year-old male with a history of unprovoked deep vein thrombosis (DVT) incidentally found to have a mediastinal lesion between the left subclavian and left common carotid artery, which was growing in size. Resection was offered after a thorough workup. A robotic approach was offered and attempted; however, this was aborted in the setting of arterial bleeding. The patient ultimately required hemisternotomy and resection with postoperative complications of hydropneumothorax requiring tube thoracostomy and pulmonary embolism requiring therapeutic anticoagulation.  While both ultimately had successful resection, the older patient with sternotomy suffered no postoperative complications as compared to the younger male with the hemisternotomy. Nonetheless, this series highlights two cases where an open approach was required through sternotomy and hemisternotomy with successful resection of mediastinal masses.

Indexed as

general thoracic surgerymediastinum malignancyparagangliomasternotomysubsternal goiter

Identifiers

PMID41181743
PMCPMC12579371

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.