ArticleWorld journal of cardiology2025
Frailty status and outcomes of percutaneous coronary intervention in elderly patients with non-ST-elevation myocardial infarction.
Article in World journal of cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of frailty on post-procedural adverse outcomes in older adults aged ≥75 years undergoing percutaneous coronary intervention: a systematic review of observational studies.Frontiers in medicine · 2026Pooled it
- Frailty in elderly patients with non-ST elevation myocardial infarction: Balancing the risks and benefits of percutaneous coronary intervention.World journal of cardiology · 2026Article
- Frailty first: Rethinking invasive strategies for elderly patients with non-ST-elevation myocardial infarction.World journal of cardiology · 2026Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-ST-elevation myocardial infarction (NSTEMI) is a prevalent acute coronary syndrome among the elderly, a population often underrepresented in clinical trials. Frailty, a marker of physiologic vulnerability, may influence the risks and benefits of percutaneous coronary intervention (PCI) in these patients.
aimTo evaluate the impact of frailty status on in-hospital outcomes among patients aged ≥ 75 years with NSTEMI undergoing PCI.
methodsWe conducted a retrospective cohort study using the 2021-2022 National Inpatient Sample to evaluate the impact of frailty on in-hospital outcomes among NSTEMI patients aged ≥ 75 years undergoing PCI. Patients were stratified into three frailty categories using the Hospital Frailty Risk Score. Multivariable logistic and generalized linear models with interaction terms assessed the association between frailty and clinical outcomes.
resultsAmong 456690 NSTEMI admissions, 37.95%, 50.71%, and 11.34% were categorized as low, intermediate, and high frailty, respectively. PCI use declined with increasing frailty (35.0% in low
conclusionIn elderly NSTEMI patients, PCI conferred a survival benefit across all frailty strata, although with a diminishing magnitude as frailty increased. Frailty correlated with increased complications and healthcare resource utilization.
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