Evidence map›Paper›PMID 41181532›Full record

ArticleWorld journal of gastrointestinal endoscopy2025

Risk scoring system combined with traditional Chinese medicine constitution identification improves colorectal advanced neoplasms screening effectiveness for early colonoscopy.

Qing-Hua Liu, Yue Hou, Shu Li, Yun-Long Gu, Chen-Xi Huang, Qian Kang, Ya-Jing Fan, Ling-Qin Zhu, Li Sun, Rui-Cheng Men and 5 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Qing-Hua LiuDepartment of Gastroenterology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Yue HouDepartment of Gastroenterology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Shu LiDepartment of Gastroenterology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Yun-Long GuDepartment of Gastroenterology, Wuhai Hospital of Traditional Chinese and Mongolian Medicine, Wuhai 016000, Inner Mongolia Autonomous Region, China.
Chen-Xi HuangDepartment of Physical Examination Center, The Affiliated Panjin Liaohe Oilfield Gem Flower Hospital of Jinzhou Medical University, Panjin 124120, Liaoning Province, China.
Qian KangDepartment of Gastroenterology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Ya-Jing FanDepartment of Gastroenterology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Ling-Qin ZhuDepartment of Gastroenterology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Li SunDepartment of Gastroenterology, Wuhai Hospital of Traditional Chinese and Mongolian Medicine, Wuhai 016000, Inner Mongolia Autonomous Region, China.
Rui-Cheng MenDepartment of Gastroenterology, Wuhai Hospital of Traditional Chinese and Mongolian Medicine, Wuhai 016000, Inner Mongolia Autonomous Region, China.
Xiao-Yan LiDepartment of Gastroenterology, Wuhai Hospital of Traditional Chinese and Mongolian Medicine, Wuhai 016000, Inner Mongolia Autonomous Region, China.
Hui WangDepartment of Urology, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine, Nanjing Medical University, Taizhou 225300, Jiangsu Province, China.
Xiu-Ying WeiDepartment of Gastroenterology, Wuhai Hospital of Traditional Chinese and Mongolian Medicine, Wuhai 016000, Inner Mongolia Autonomous Region, China.
Zhao-Gang SunDepartment of Gastroenterology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
Yu-Qi HeDepartment of Gastroenterology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Asia-Pacific Colorectal Screening (APCS) score was designed with the purpose of distinguishing individuals at high risk (HR) for colorectal advanced neoplasia (AN). Traditional Chinese medicine (TCM) constitution was also linked with colorectal cancer (CRC).

aimTo integrate the APCS score with TCM constitution identification as a new algorithm to screen for CRC.

methodsA cross-sectional multicenter study was carried out in three hospitals, enrolling 1430 patients who were asymptomatic and undergoing screening colonoscopy from 2022 to 2023. Patients were considered to have average risk, moderate risk, or HR with their APCS score. Odd ratios assessed the relationship between TCM constitution and disease progression. A TCM constitution risk score was created. The sensitivity and specificity of the new algorithm were calculated to evaluate diagnostic performance in detecting advanced adenoma (AA), CRC, and AN.

resultsOf the 1430 patients, 370 (25.9%) were categorized as average risk, 755 (52.8%) as moderate risk, and 305 (21.3%) as HR. Using the combined APCS score and the TCM constitution (damp-heat, qi-deficiency, yang-deficiency, phlegm-dampness, and inherited special constitution as positive) algorithm, 72.2% of patients with AA and 73.7% of patients with AN were detected. Compared with the APCS score alone, the new algorithm significantly improved the sensitivity for screening AA [72.2%, 95% confidence interval (CI): 64.4%-80.0%

conclusionThe combination of APCS and TCM constitution identification questionnaires was valuable in identifying Chinese individuals who were asymptomatic for colorectal screening prioritization.

Indexed as

Asia-Pacific Colorectal Screening scoreColon cancerColonoscopyScreeningTraditional Chinese medicine constitution identification

Identifiers

PMID41181532
PMCPMC12576620

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.