Evidence map›Paper›PMID 41181456›Full record

ArticleAnnals of medicine and surgery (2012)2025

AI-powered CT imaging for early detection of subclinical pulmonary fibrosis in antisynthetase syndrome: a new era in autoimmune lung diagnostics.

Asiya Zubair, Ali Hamza, Maliha Khalid, Muhammad Talha, Aminath Waafira

Abstract readLetter
In one paragraph

Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Asiya ZubairJinnah Sindh Medical University, Karachi, Pakistan.ORCID https://orcid.org/0009-0002-7586-9053
Ali HamzaMayo Hospital, Lahore, Pakistan.ORCID https://orcid.org/0009-0002-1699-1104
Maliha KhalidJinnah Sindh Medical University, Karachi, Pakistan.ORCID https://orcid.org/0009-0001-3413-2752
Muhammad TalhaKing Edward Medical University, Lahore, Pakistan.
Aminath WaafiraThe Maldives National University, Malé, Maldives.ORCID https://orcid.org/0009-0000-3283-1982

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antisynthetase syndrome (ASS), a rare autoimmune condition, often leads to subclinical pulmonary fibrosis (PF) that remains undetected until irreversible damage occurs. High-resolution computed tomography (HRCT) is pivotal in early PF detection, yet interpretation inconsistencies remain a challenge. Artificial intelligence (AI) and machine learning (ML) applications-such as multiple feature texture analysis, CALIPER, and deep learning segmentation tools-are revolutionizing lung imaging by minimizing observer variability, enhancing early diagnosis, and uncovering novel imaging biomarkers. While promising, the adoption of AI for rare disease diagnostics like ASS requires overcoming data limitations, bias, and validation hurdles. This letter calls for integrated genomic-imaging models, open-access repositories, and international data collaboration to effectively translate AI advancements into routine diagnostics for autoimmune lung disease.

Indexed as

antisynthetase syndromeartificial intelligenceCT imagingpulmonary fibrosis

Identifiers

PMID41181456
PMCPMC12577803

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.